Teaching NeuroImages: Pneumocephalus due to bacterial meningitis
Ako Dara Hama-Amin, MD,
H. Jacobus Gilhuis, MD, PhD and
Peter Portegies, MD, PhD
From the Department of Neurology (A.D.H.-A.), Haga Hospital, The Hague; Department of Neurology (H.J.G.), Reinier de Graaf Gasthuis Hospital, Delft; and Department of Neurology (P.P.), Onze Lieve Vrouwe Gasthuis Hospital, Amsterdam, The Netherlands.
Address correspondence and reprint requests to Dr. A. Dara Hama-Amin, Department of Neurology, Haga Hospital, Leyweg 275, 2545 CH The Hague, The Netherlands akodara{at}hotmail.com
A 51-year-old man presented with headache and confusion. Onexamination, he was somnolent with meningeal signs. CranialCT scan demonstrated diffuse intracranial air (figure). CSFrevealed white blood cell count of 11,850 cells/mm3. Gram stainshowed Gram-negative rods. No organisms were detected on CSFculture, probably due to the use of antibiotics for pneumonia.He died shortly afterwards.
Figure Nonenhanced cranial CT scan showing multiple diffuse air pockets in the subarachnoidal space, parenchyma, and ventricles in a patient with meningitis due to Gram-negative rods
Pneumocephalus is usually caused by trauma or surgery.1 Bacterialmeningitis is a rare cause of pneumocephalus. The majority ofpatients do not survive.2
Markham JW. The clinical features of pneumocephalus based upon a survey of 284 cases with report of 11 additional cases. Acta Neurochir 1967;16:1–78.[Medline]
Tanaka T, Takagi D, Takeyama N, Kitazawa Y. "Spontaneous" pneumocephalus associated with aerobic bacteremia. Clin Imaging 1989;13:134–139.[Medline]