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Mortality from combined carotid endarterectomy and coronary artery bypass surgery in the US

From the Departments of Neurology (R.M.D.) and Preventive Medicine and Public Health (S.M.L.), University of Kansas Medical Center, Kansas City, KS.

Address correspondence and reprint requests to Dr. Richard M. Dubinsky, Department of Neurology, University of Kansas Medical Center, Mail Stop 2012, 3599 Rainbow Blvd., Kansas City, KS 66160; e-mail: rdubinsky{at}safetyresearch.com or rdubinsk{at}kumc.edu

We determined hospital mortality and postoperative stroke rates after combined carotid endarterectomy (CEA) and coronary artery bypass graft surgery (CABG) vs CABG alone, using the US Nationwide Inpatient Sample. CEA–CABG combined was 1.06%. After correcting for comorbidities, the odds ratio for postoperative stroke or death for CEA–CABG was 1.38 (95% CI 1.27 to 1.50) vs CABG. With the increase in postoperative stroke and death, a randomized, controlled clinical trial of combined CEA–CABG is indicated.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the January 16 issue to find the title link for this article.

Disclosure: The authors report no conflicts of interest.

Presented at the 58th Annual Meeting of the American Academy of Neurology, April 4, 2006.

Received April 10, 2006. Accepted in final form August 22, 2006.

See also page 187

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