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Tracheostomy can fatally exacerbate sleep-disordered breathing in multiple system atrophy

From the Department of Neurology (K.J., K.C., N.A.), Iwate National Hospital, Sendai Sleep Clinic (S.O.), Department of Neurology (T.K., A.O., H.N.), Kohnan Hospital, Department of Neurology (Y.I.), Tohoku University School of Medicine, and Department of Neurology (H.O.), Nishitaga National Hospital, Japan.

Address correspondence and reprint requests to Dr. K. Jin, Department of Neurology, Iwate National Hospital, 48 Dorotayama-shita, Yamanome, Ichinoseki, Iwate 021-0056, Japan jink{at}em.neurol.med.tohoku.ac.jp

Tracheostomy has been employed to release the airway obstruction at the glottic level and to prevent sudden death in patients with multiple system atrophy (MSA). However, sudden death is possible even after tracheostomy. Nocturnal polysomnography showed that the apnea–hypopnea index became higher after tracheostomy, and all tracheostomized patients had frequent central sleep apneas.

Supplemental data at www.neurology.org

Supported by grants-in-aid for Scientific Research (15659206) from the Ministry of Education, Science, and Culture.

Disclosure: The authors report no conflicts of interest.

Received February 10, 2006. Accepted in final form December 28, 2006.

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				M. H. Silber, T . Shimohata, T . Ozawa, H . Nakayama, M . Tomita, M . Nishizawa, K. Jin, H. Onodera, and Y. Itoyama Tracheostomy can fatally exacerbate sleep-disordered breathing in multiple system atrophy. Neurology, March 18, 2008; 70(12): 980 - 981. [Full Text] [PDF]

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