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NEUROLOGY 2005;64:S12-S20
© 2005 American Academy of Neurology

Neurology supplements are not peer-reviewed. Information contained in Neurology supplements represent the opinions of the authors and are not endorsed by nor do they reflect the views of the American Academy of Neurology, Editor-in-Chief, or Associate Editors of Neurology.

Sleep issues in Parkinson’s disease

Charles H. Adler, MD, PhD and Michael J. Thorpy, MD

From the Parkinson’s Disease and Movement Disorders Center, Mayo Clinic Scottsdale, Scottsdale, Arizona. USA (Dr. Adler), and the Sleep-Wake Disorder Center, Montefiore Medical Center, Bronx, New York, USA (Dr. Thorpy).

Address correspondence to Dr. Charles H. Adler, Parkinson’s Disease and Movement Disorders Center, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, AZ 85256: e-mail: cadler{at}mayo.edu

Sleep disturbances in patients with Parkinson’s disease (PD) are common, are often severe, and are typically underrecognized and ineffectively treated. After the recognition that some patients with PD could fall asleep unexpectedly when driving, with resulting dangerous consequences, it became evident not only that PD medications might be partly responsible but that there were many additional factors contributing to sleep disturbance in these patients. This review discusses the myriad sleep disorders seen in patients with PD, presents their diagnostic features, and gives recommendations on their management. Effective management of sleep disturbances and excessive daytime sleepiness can greatly improve the quality of life for patients with PD.

Publication of this supplement was made possible by an educational grant from GlaxoSmithKline. The sponsor has provided C.H.A. with the following financial support: honoraria during his career (in excess of $10,000) and grant support. The sponsor has provided M.J.T. with the following financial support: an honorarium for his participation in this project and other honoraria during his career (in excess of $10,000).




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