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Neurology 2003;61:395-397
© 2003 American Academy of Neurology
Brief Communications

Rasmussen encephalitis associated with Parry–Romberg syndrome

J.R. Shah, MD, C. Juhász, MD, W.J. Kupsky, MD, E. Asano, MD, S. Sood, MD, D. Fain, MD and H.T. Chugani, MD

From the Departments of Neurology (Drs. Shah and Chugani), Pathology (Dr. Kupsky), Pediatrics (Drs. Juhász, Asano, and Chugani), Radiology (Dr. Chugani), and Neurosurgery (Dr. Sood), Harper University Hospital and Children’s Hospital of Michigan, Detroit Medical Center, Wayne State University School of Medicine, Detroit, MI; and Bronson Medical Center (Dr. Fain), Kalamazoo, MI.

Address correspondence and reprint requests to Dr. Jagdish R. Shah, 8D University Health Center, Department of Neurology, Detroit Medical Center, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI 48201; e-mail: jshah{at}med.wayne.edu

Parry–Romberg syndrome is a rare disorder associated with unilateral facial atrophy involving skin, subcutaneous tissue, skeletal muscle, and bone. Occasionally, there is CNS involvement with epilepsy being the most common CNS manifestation. The authors report a child with Parry–Romberg syndrome with a course strongly suggestive of Rasmussen encephalitis. The boy underwent hemispherectomy, and pathology showed the typical findings of Rasmussen encephalitis, suggesting that these two conditions may share common etiologic factors.




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