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Neurology 2002;59:611-613
© 2002 American Academy of Neurology
Brief Communications

Comparison of sensory testing on different toe surfaces: Implications for neuropathy screening

Dimitri Dimitrakoudis, MD and Vera Bril, MD FRCPC

From the University Health Network, Toronto General Hospital, University of Toronto, Ontario, Canada.

Address correspondence and reprint requests to Dr. Vera Bril, EN 11-209, Toronto General Hospital, University Health Network, 200 Elizabeth St., Toronto, Ontario, Canada; e-mail: vera.bril{at}utoronto.ca

Successful screening for neuropathy in patients with diabetes is available using the 10 g Semmes–Weinstein monofilament (Mid-Delta Health Systems, Inc., Belzoni, MS) (touch/pressure sensation) and the Neurothesiometer (Horwell Scientific, London, UK; vibration perception threshold). In healthy volunteers and patients with a broad range of diabetic sensorimotor neuropathy, we show that the predictive value of either test for diabetic sensorimotor neuropathy depends on the toe surface tested. These results establish the importance of standardized screening methods for diabetic sensorimotor neuropathy in the clinic and in clinical research trials.




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