Neurology
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Right arrow Amyotrophic lateral sclerosis
Neurology 2002;58:485-487
© 2002 American Academy of Neurology
Brief Communications

Gastrostomy insertion in ALS patients with low vital capacity: Respiratory support and survival

Susan Gregory, MD, Andrew Siderowf, MD, Ame L. Golaszewski, MS RD and Leo McCluskey, MD

From the Department of Medicine (Dr. Gregory), Pennsylvania Hospital; Department of Clinical Nutrition Support Services (A.L. Golaszewski), Hospital of the University of Pennsylvania; and Department of Neurology (Drs. Siderowf and McCluskey), University of Pennsylvania, Philadelphia.

Address correspondence and reprint requests to Dr. Leo McCluskey, Penn Neurological Institute, 330 South 9th Street, Philadelphia, PA 19107; e-mail: lfmcclusky{at}pahosp.com

The authors evaluated their uncontrolled, retrospective experience with 33 patients with ALS with erect or supine forced vital capacity less than 50% predicted who underwent attempted percutaneous endoscopic gastrostomy (PEG) tube placement using noninvasive positive pressure ventilation and oxygen support and conscious sedation anesthesia. Gastrostomy tubes were successfully placed in all patients. Mean survival was 211 days with most patients (67%) surviving more than 180 days. Forced vital capacity at the time of PEG placement did not predict survival.






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