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Neurology 2002;58:1849-1852 © 2002 American Academy of Neurology Brief Communications History of head trauma and risk of intracranial meningioma: Population-based case-control studyFrom the Departments of Epidemiology (L. Phillips, and Drs. Koepsell, Kukull, and Longstreth), Biostatistics (Dr. van Belle), Health Services (Dr. Koepsell), Environmental Health (Dr. van Belle), and Neurology (Dr. Longstreth and J.-A. Gehrels), University of Washington, Seattle. Address correspondence and reprint requests to Dr. W.T. Longstreth, Jr., Department of Neurology, Box 359775, Harborview Medical Center, 325 9th Avenue, Seattle, WA 98104-2420; e-mail: wl{at}u.washington.edu A population-based case-control study in western Washington state was performed to assess the relation between head trauma and meningioma. Based on 200 case and 400 control subjects, head trauma was associated with an increased risk of meningioma (odds ratio = 1.83; 95% CI = 1.28, 2.62), especially head traumas occurring 10 to 19 years before reference date (odds ratio = 4.33; 95% CI = 2.06, 9.10). A dose-response relationship was present for number, but not severity, of head traumas. Whether the associations observed in this study are causal remains unclear. This article has been cited by other articles:
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