| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
From the Department of Neurology, Stroke Unit (Drs. Hénon, Durieu, Guerouaou, and Leys), and Memory Clinic (Drs. Hénon, Pasquier, and Lebert), University of Lille, France.
Address correspondence and reprint requests to Dr. Hilde Hénon, Department of Neurology, Stroke Unit, Hôpital Roger Salengro, F-59037 Lille, France; e-mail: hhenon{at}chru-lille.fr
Objective: To evaluate the 3-year incidence of poststroke dementia (PSD) and the influence of prestroke cognitive decline. Methods: The authors evaluated prestroke cognitive functions in 202 consecutive stroke patients 
40 years old using the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), with a cut-off of 104 for the diagnosis of dementia. Six months and then annually after stroke, dementia was reassessed. The diagnosis of dementia was based on the International Classification of Diseases, 10th revision criteria in survivors who underwent a visit with a neurologist, or on the IQCODE score obtained by telephone contact with the family in survivors who did not. Statistics were performed using life-table methods. Results: Thirty-three patients were excluded because of prestroke dementia. In the 169 remaining patients, the cumulative proportion of patients with dementia was 28.5% at the end of the follow-up period, with most of PSD occurring during the first 6 months. Using multivariate analysis, independent predictors of PSD were aging, preexisting cognitive decline, severity of deficit at admission, diabetes mellitus, and silent infarcts. Leukoaraiosis was an independent predictor of PSD when prestroke cognitive decline was not taken into account. The presumed etiology of dementia was vascular dementia (VaD) in two-thirds of patients and AD in one-third. Conclusions: The risk of PSD is high, and increased in patients with prestroke cognitive decline, with about one-third of patients meeting the criteria for AD and two-thirds meeting the criteria for VaD. These results confirm that, in stroke patients, an underlying degenerative pathology may play a role in the development of PSD.
This article has been cited by other articles:
|
|
 |
|
  A. Jaillard, B. Naegele, S. Trabucco-Miguel, J. F. LeBas, and M. Hommel Hidden Dysfunctioning in Subacute Stroke * Supplemental Appendix Stroke, July 1, 2009; 40(7): 2473 - 2479. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Zarei, J. S. Damoiseaux, C. Morgese, C. F. Beckmann, S. M. Smith, P. M. Matthews, P. Scheltens, S. A.R.B. Rombouts, and F. Barkhof Regional White Matter Integrity Differentiates Between Vascular Dementia and Alzheimer Disease Stroke, March 1, 2009; 40(3): 773 - 779. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. W. Simpkins, E. Perez, Xiaofei Wang, ShaoHua Yang, Yi Wen, and M. Singh Review: The potential for estrogens in preventing Alzheimer's disease and vascular dementia Therapeutic Advances in Neurological Disorders, January 1, 2009; 2(1): 31 - 49. [Abstract] [PDF]
|
|
|
|
|
|
M. O'Sullivan Prestroke Cognitive Function and Cerebrovascular Disease: If They Interact, It May Not Be Through Symptomatic Stroke Stroke, January 1, 2008; 39(1): 3 - 4. [Full Text] [PDF]
|
|
|
|
|
|
C. Reitz, M. J. Bos, A. Hofman, P. J. Koudstaal, and M. M.B. Breteler Prestroke Cognitive Performance, Incident Stroke, and Risk of Dementia: The Rotterdam Study Stroke, January 1, 2008; 39(1): 36 - 41. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D S KNOPMAN Cerebrovascular disease and dementia Br. J. Radiol., December 1, 2007; 80(Special_Issue_2): S121 - S127. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Cullen, B. O'Neill, J. J Evans, R. F Coen, and B. A Lawlor A review of screening tests for cognitive impairment J. Neurol. Neurosurg. Psychiatry, August 1, 2007; 78(8): 790 - 799. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Cordonnier, H. Henon, P. Derambure, F. Pasquier, and D. Leys Early epileptic seizures after stroke are associated with increased risk of new-onset dementia J. Neurol. Neurosurg. Psychiatry, May 1, 2007; 78(5): 514 - 516. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Pasquini, D Leys, M Rousseaux, F Pasquier, and H Henon Influence of cognitive impairment on the institutionalisation rate 3 years after a stroke J. Neurol. Neurosurg. Psychiatry, January 1, 2007; 78(1): 56 - 59. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Gamaldo, A. Moghekar, S. Kilada, S. M. Resnick, A. B. Zonderman, and R. O'Brien Effect of a clinical stroke on the risk of dementia in a prospective cohort Neurology, October 24, 2006; 67(8): 1363 - 1369. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. S. Knopman Dementia and Cerebrovascular Disease Mayo Clin. Proc., February 1, 2006; 81(2): 223 - 230. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C Cordonnier, H Henon, P Derambure, F Pasquier, and D Leys Influence of pre-existing dementia on the risk of post-stroke epileptic seizures J. Neurol. Neurosurg. Psychiatry, December 1, 2005; 76(12): 1649 - 1653. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. L. Lopez, L. H. Kuller, J. T. Becker, W. J. Jagust, S. T. DeKosky, A. Fitzpatrick, J. Breitner, C. Lyketsos, C. Kawas, and M. Carlson Classification of vascular dementia in the Cardiovascular Health Study Cognition Study Neurology, May 10, 2005; 64(9): 1539 - 1547. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Solfrizzi, F. Panza, A. M. Colacicco, A. D'Introno, C. Capurso, F. Torres, F. Grigoletto, S. Maggi, A. Del Parigi, E. M. Reiman, et al. Vascular risk factors, incidence of MCI, and rates of progression to dementia Neurology, November 23, 2004; 63(10): 1882 - 1891. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S M C Rasquin, F R J Verhey, R J van Oostenbrugge, R Lousberg, and J Lodder Demographic and CT scan features related to cognitive impairment in the first year after stroke J. Neurol. Neurosurg. Psychiatry, November 1, 2004; 75(11): 1562 - 1567. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. K. Srikanth, J. F.I. Anderson, G. A. Donnan, M. M. Saling, E. Didus, R. Alpitsis, H. M. Dewey, R. A.L. Macdonell, and A. G. Thrift Progressive dementia after first-ever stroke: A community-based follow-up study Neurology, September 14, 2004; 63(5): 785 - 792. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Altieri, V. Di Piero, M. Pasquini, M. Gasparini, N. Vanacore, E. Vicenzini, and G. L. Lenzi Delayed poststroke dementia: A 4-year follow-up study Neurology, June 22, 2004; 62(12): 2193 - 2197. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. V. Bowler Editorial Comment--Dementia After Stroke Stroke, June 1, 2004; 35(6): 1268 - 1269. [Full Text] [PDF]
|
|
|
|
|
|
C. S. Ivan, S. Seshadri, A. Beiser, R. Au, C. S. Kase, M. Kelly-Hayes, and P. A. Wolf Dementia After Stroke: The Framingham Study Stroke, June 1, 2004; 35(6): 1264 - 1268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. K. Tang, S. S.M. Chan, H. F.K. Chiu, G. S. Ungvari, K. S. Wong, T. C.Y. Kwok, V. Mok, K.T. Wong, P. S. Richards, and A.T. Ahuja Frequency and Determinants of Poststroke Dementia in Chinese Stroke, April 1, 2004; 35(4): 930 - 935. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Verdelho, H. Henon, F. Lebert, F. Pasquier, and D. Leys Depressive symptoms after stroke and relationship with dementia: A three-year follow-up study Neurology, March 23, 2004; 62(6): 905 - 911. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Henon, P. Vroylandt, I. Durieu, F. Pasquier, and D. Leys Leukoaraiosis More Than Dementia Is a Predictor of Stroke Recurrence Stroke, December 1, 2003; 34(12): 2935 - 2940. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Black, G. C. Roman, D. S. Geldmacher, S. Salloway, J. Hecker, A. Burns, C. Perdomo, D. Kumar, and R. Pratt Efficacy and Tolerability of Donepezil in Vascular Dementia: Positive Results of a 24-Week, Multicenter, International, Randomized, Placebo-Controlled Clinical Trial Stroke, October 1, 2003; 34(10): 2323 - 2330. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-H. Lin, R.-T. Lin, C.-T. Tai, C.-L. Hsieh, S.-F. Hsiao, and C.-K. Liu Prediction of poststroke dementia Neurology, August 12, 2003; 61(3): 343 - 348. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. E. Vermeer, N. D. Prins, T. den Heijer, A. Hofman, P. J. Koudstaal, and M. M.B. Breteler Silent Brain Infarcts and the Risk of Dementia and Cognitive Decline N. Engl. J. Med., March 27, 2003; 348(13): 1215 - 1222. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. S. Knopman, W. A. Rocca, R. H. Cha, S. D. Edland, and E. Kokmen Survival Study of Vascular Dementia in Rochester, Minnesota Arch Neurol, January 1, 2003; 60(1): 85 - 90. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Verghese, R. B. Lipton, C. B. Hall, G. Kuslansky, M. J. Katz, and H. Buschke Abnormality of Gait as a Predictor of Non-Alzheimer's Dementia N. Engl. J. Med., November 28, 2002; 347(22): 1761 - 1768. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. W. Desmond, J. T. Moroney, M. Sano, Y. Stern, and J. G. Merino Incidence of Dementia After Ischemic Stroke: Results of a Longitudinal Study * Editorial Comment Stroke, September 1, 2002; 33(9): 2254 - 2262. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
