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Neurology 2001;57:348-351
© 2001 American Academy of Neurology
Brief Communications

Spectrum of myelopathies in HIV seropositive South African patients

A. I. Bhigjee, MD;, S. Madurai, MSc;, P.L.A. Bill, FRCP;, V. Patel, FCN;, P. Corr, FRCR;, M.N. Naidoo, MTech;, W.M. Gopaul, MTech;, A. Smith, FRCPath; and D. York, PhD

From the Departments of Neurology (Dr. Bhigjee, S. Madurai, Dr. Bill, and V. Patel), Radiology (Dr. Corr), and Virology (M. Naidoo, W. Gopaul, and Drs. Smith and York), University of Natal, South Africa.

Address correspondence and reprint requests to Professor A.I. Bhigjee, SubDepartment of Neurology, Pvt Bag, JACOBS, 4026, South Africa; e-mail: Bhigjee{at}mu.ac.za

The authors determined the cause of myelopathies in 33 HIV seropositive individuals in KwaZulu/Natal, South Africa. The main associations were with human T-cell lymphotrophic virus–I, tuberculosis, herpes zoster, and syphilis. A novel association with probable bilharziasis was noted. Only one case of vacuolar myelopathy was identified. Opportunistic infections will probably persist until routine antiretroviral therapy becomes widely available in South Africa.




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