| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
From the Stroke Service, Department of Neurology (Drs. Rordorf, Koroshetz, Ezzeddine, and Buonanno), Massachusetts General Hospital, Boston; and Stroke Service (Dr. Segal), Cornell University Medical Center, New York.
Address correspondence and reprint requests to Dr. G. Rordorf, Department of Neurology, Blake 1291, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114; e-mail: grordorf{at}partners.org
The aim of this pilot study was to determine whether the use of induced hypertension in acute stroke is feasible and associated with neurologic improvement. Phenylephrine was used to raise the systolic blood pressure in patients with acute stroke by 20%, not to exceed 200 mmHg. Of 13 patients treated, 7 improved by 2 points on the NIH Stroke Scale. No systemic or neurologic complications were seen. The authors conclude that induced hypertension in acute stroke is feasible and likely safe and can improve the neurologic examination in some patients.
This article has been cited by other articles:
|
|
 |
|
  R. Delgado-Mederos, M. Ribo, A. Rovira, M. Rubiera, J. Munuera, E. Santamarina, P. Delgado, O. Maisterra, J. Alvarez-Sabin, and C. A. Molina Prognostic significance of blood pressure variability after thrombolysis in acute stroke Neurology, August 19, 2008; 71(8): 552 - 558. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Hillis, L. Gold, V. Kannan, L. Cloutman, J. T. Kleinman, M. Newhart, J. Heidler-Gary, C. Davis, E. Aldrich, R. Llinas, et al. Site of the ischemic penumbra as a predictor of potential for recovery of functions Neurology, July 15, 2008; 71(3): 184 - 189. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. K. Shin, M. Nishimura, P. B. Jones, H. Ay, D. A. Boas, M. A. Moskowitz, and C. Ayata Mild Induced Hypertension Improves Blood Flow and Oxygen Metabolism in Transient Focal Cerebral Ischemia Stroke, May 1, 2008; 39(5): 1548 - 1555. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. E. Marik and J. Varon Hypertensive Crises: Challenges and Management Chest, June 1, 2007; 131(6): 1949 - 1962. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al. Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation, May 22, 2007; 115(20): e478 - e534. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al. Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists Stroke, May 1, 2007; 38(5): 1655 - 1711. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. E. Hillis, J. T. Kleinman, M. Newhart, J. Heidler-Gary, R. Gottesman, P. B. Barker, E. Aldrich, R. Llinas, R. Wityk, and P. Chaudhry Restoring Cerebral Blood Flow Reveals Neural Regions Critical for Naming J. Neurosci., August 2, 2006; 26(31): 8069 - 8073. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K. Mistri, T. G. Robinson, and J. F. Potter Pressor Therapy in Acute Ischemic Stroke: Systematic Review Stroke, June 1, 2006; 37(6): 1565 - 1571. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Chalela, B. Dunn, J. W. Todd, and S. Warach Induced hypertension improves cerebral blood flow in acute ischemic stroke Neurology, June 14, 2005; 64(11): 1979 - 1979. [Full Text] [PDF]
|
|
|
|
|
|
H. P. Mattle, L. Kappeler, M. Arnold, U. Fischer, K. Nedeltchev, L. Remonda, S. M. Jakob, and G. Schroth Blood Pressure and Vessel Recanalization in the First Hours After Ischemic Stroke Stroke, February 1, 2005; 36(2): 264 - 268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. E. Marik Renal Dose Norepinephrine! Chest, August 1, 2004; 126(2): 335 - 337. [Full Text] [PDF]
|
|
|
|
|
|
P. H. Lee, S. -H. Oh, O. Y. Bang, S. -Y. Joo, I. S. Joo, and K. Huh Infarct patterns in atherosclerotic middle cerebral artery versus internal carotid artery disease Neurology, April 27, 2004; 62(8): 1291 - 1296. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. S. Marzan, H. -J. Hungerbuhler, A. Studer, R. W. Baumgartner, and D. Georgiadis Feasibility and safety of norepinephrine-induced arterial hypertension in acute ischemic stroke Neurology, April 13, 2004; 62(7): 1193 - 1195. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Gupta, H.C. Schumacher, S. Mangla, P.M. Meyers, H. Duong, A.G. Khandji, R.S. Marshall, J.P. Mohr, and J. Pile-Spellman Urgent endovascular revascularization for symptomatic intracranial atherosclerotic stenosis Neurology, December 23, 2003; 61(12): 1729 - 1735. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Hillis, R. J. Wityk, P. B. Barker, J. A. Ulatowski, and M. A. Jacobs Change in Perfusion in Acute Nondominant Hemisphere Stroke May Be Better Estimated by Tests of Hemispatial Neglect Than by the National Institutes of Health Stroke Scale Stroke, October 1, 2003; 34(10): 2392 - 2396. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. H. Messerli, D. F. Hanley Jr., and P. B. Gorelick Blood pressure control in stroke patients: What should the consulting neurologist advise? Neurology, July 9, 2002; 59(1): 23 - 25. [Full Text] [PDF]
|
|
|
|
|
|
M. A. Ezzeddine, M. H. Lev, C. T. McDonald, G. Rordorf, J. Oliveira-Filho, F. G. Aksoy, J. Farkas, A. Z. Segal, L. H. Schwamm, R. G. Gonzalez, et al. CT Angiography With Whole Brain Perfused Blood Volume Imaging: Added Clinical Value in the Assessment of Acute Stroke Stroke, April 1, 2002; 33(4): 959 - 966. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Schwarz, D. Georgiadis, A. Aschoff, and S. Schwab Effects of Induced Hypertension on Intracranial Pressure and Flow Velocities of the Middle Cerebral Arteries in Patients With Large Hemispheric Stroke Stroke, April 1, 2002; 33(4): 998 - 1004. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
