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Neurology 2000;55:1385-1388
© 2000 American Academy of Neurology
Brief Communications

Epidemiology of inclusion body myositis in the Netherlands: A nationwide study

U. A. Badrising, MD, M. Maat-Schieman, MD, PhD, S. G. van Duinen, MD, PhD, F. Breedveld, MD, PhD, P. van Doorn, MD, PhD, B. van Engelen, MD, PhD, F. van den Hoogen, MD, PhD, J. Hoogendijk, MD, PhD, C. Höweler, MD, PhD, A. de Jager, MD, PhD, F. Jennekens, MD, PhD, P. Koehler, MD, PhD, H. van der Leeuw, MD, M. de Visser, MD, PhD, J. J. Verschuuren, MD, PhD and A. R. Wintzen, MD, PhD

From the Departments of Neurology (Drs. Badrising, Maat-Schieman, Verschuuren, and Wintzen), Pathology (Dr. Van Duinen), and Rheumatology (Dr. Breedveld), Leiden University Medical Center; the Department of Neurology (Dr. van Doorn), University Hospital, Rotterdam; the Department of Neurology (Dr. van Engelen) and the Department of Rheumatology (Dr. van den Hoogen), University Hospital, Nijmegen; the Department of Neurology (Dr. Höweler), University Hospital, Maastricht; the Department of Neurology (Dr. Hoogendijk), University Medical Center, Utrecht; the Department of Neurology (Dr. de Jager), University Hospital, Groningen; the Department of Neurology (Dr. Koehler), De Wever Hospital, Heerlen; the Department of Neurology (Dr. van der Leeuw), Maria Hospital, Tilburg; Interuniversitair Steunpunt Neuromusculair Onderzoek (Dr. Jennekens), Baarn; and the Department of Neurology (Dr. de Visser), Academic Medical Center, Amsterdam, the Netherlands.

Address correspondence and reprint request to Dr. U.A. Badrising, Department of Neurology, K5Q, Leiden University Medical Center, POB 9600, 2300 RC Leiden, the Netherlands; e-mail: ubadrising{at}neurology.azl.nl

Epidemiologic data on inclusion body myositis (IBM) are scarce, and possibly biased, because they are derived from larger neuromuscular centers. The present nationwide collaborative cross-sectional study, which culminated on July 1, 1999, resulted in identification of 76 patients with IBM and the establishment of a prevalence of 4.9 patients with IBM per million inhabitants in the Netherlands. Several discrepancies suggest that this may be an underestimation. The most frequently identified pitfall in diagnosing IBM was an erroneous diagnosis of polymyositis or motor neuron disease.




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