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From the Institute of Neurology (Drs. Gambardella, Bono, Oliveri, Valentino, Zappia, Quattrone, and Aguglia), School of Medicine Catanzaro, Catanzaro; Institute of Experimental Medicine and Biotechnology (Drs. Gambardella, Cittadella, Oliveri, and Quattrone), National Research Council, Piano Lago di Mangone-Cosenza; and Laboratory of Cytopathology (Dr. Pasquinelli), Policlinico S. Orsola Malpighi, Bologna, Italy.
Address correspondence and reprint requests to Dr. Antonio Gambardella, Cattedra ed U.O. di Neurologia, Facoltà di Medicine e Chirurgia, Via Tommaso Campanella, 88100 Catanzaro, Italy.
A 64-year-old woman, who had no personal or family history of neurologic diseases, had an 18-month history of epilepsia partialis continua (EPC) associated with a moderate intellectual deterioration and subtle extrapyramidal rigidity. There was no photosensitive response. A thorough laboratory investigation was unremarkable. A biopsy of the rectal mucosa revealed abundant fingerprint profiles diagnostic of Kufs' disease (KD). Our case expands the clinical picture of KD and suggests that such a diagnosis should be considered in adult-onset EPC.
Received February 5, 1998. Accepted in final form May 29, 1998.
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