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Department of Neurology (Drs. Crino, Laskowitz, Raps, and Rostami), Hospital of the University of Pennsylvania, and Section of Neuroradiology (Dr. Zimmerman), The Children's Hospital of Philadelphia, Philadelphia, PA.
We report three patients (two children and one adult) with Guillain-Barré syndrome and magnetic resonance imaging evidence of gadolinium enhancement of the cauda equina and lumbar nerve roots. All three patients exhibited symmetric ascending paralysis and areflexia, and two (one child, one adult) suffered urinary incontinence and retention. Similar enhancement has been observed in patients with chronic inflammatory demyelinating polyneuropathy and suggests proximal nerve inflammation. Magnetic resonance imaging in Guillain-Barré syndrome and chronic imflammatory demyelinating polyneuropathy may have diagnostic utility.
Address correspondence and reprint requests to Dr. A.M. Rostami, Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104.
Received September 14, 1993. Accepted in final form January 25, 1994.
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