Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Silverman, S. E.
Right arrow Articles by Feldon, S. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Silverman, S. E.
Right arrow Articles by Feldon, S. E.
NEUROLOGY 1994;44:1814
© 1994 American Academy of Neurology

Dissociation between the detection and perception of motion in Alzheimer's disease

Scott E. Silverman, MD, Dan B. Tran, MD, Kerry M. Zimmerman, MS and Steven E. Feldon, MD

Departments of Ophthalmology (Drs. Silverman, Tran, and Feldon, and K.M. Zimmerman) and Neurological Surgery (Dr. Feldon), University of Southern California School of Medicine, and Doheny Eye Institute (Drs. Silverman, Tran, and Feldon, and K.M. Zimmerman), Los Angeles, CA.

To better understand the damage to the motion pathway that occurs in senile dementia of the Alzheimer type (SDAT), we developed a system to assess separately the conscious perception and unconscious detection of motion in patients with SDAT. Motion perception thresholds were significantly elevated in SDAT (n = 9) compared with controls (n = 12), but motion detection thresholds were normal. This dissociation between the perception and detection of motion in early SDAT parallels histologic evidence of a disconnection between primary and association visual cortices. This disconnection may underlie the severe visual perception deficits seen in SDAT.

Address correspondence and reprint requests to Dr. Steven E. Feldon, Doheny Eye Institute, 1450 San Pablo Street, Los Angeles, CA 90033.

Received December 6, 1993. Accepted in final form April 8, 1994.




This article has been cited by other articles:


Home page
 BrainHome page
M. Mapstone, D. Logan, and C. J. Duffy
Cue integration for the perception and control of self-movement in ageing and Alzheimer's disease.
Brain, November 1, 2006; 129(Pt 11): 2931 - 2944.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
V. Kavcic, R. Fernandez, D. Logan, and C. J. Duffy
Neurophysiological and perceptual correlates of navigational impairment in Alzheimer's disease
Brain, March 1, 2006; 129(3): 736 - 746.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
V. Kavcic and C. J. Duffy
Attentional dynamics and visual perception: mechanisms of spatial disorientation in Alzheimer's disease
Brain, May 1, 2003; 126(5): 1173 - 1181.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
R. W. Crow, L. B. Levin, L. LaBree, R. Rubin, and S. E. Feldon
Sweep Visual Evoked Potential Evaluation of Contrast Sensitivity in Alzheimer's Dementia
Invest. Ophthalmol. Vis. Sci., February 1, 2003; 44(2): 875 - 878.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
S. J. Tetewsky and C. J. Duffy
Visual loss and getting lost in Alzheimer's disease
Neurology, March 1, 1999; 52(5): 958 - 958.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1994 by AAN Enterprises, Inc.