HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Polo, J. M. Articles by Berciano, J. Search for Related Content PubMed PubMed Citation Articles by Polo, J. M. Articles by Berciano, J.

Treatment of cerebral aspergillosis after liver transplantation

Services of Neurology, University Hospital Marqués de Valdecilla, University of Cantabria, Santander, Spain (Drs. Polo and Berciano)
Hepato- Gastroenterology, University Hospital Marqués de Valdecilla, University of Cantabria, Santander, Spain (Drs. Fábrega and Casafont)
Infectious Diseases, University Hospital Marqués de Valdecilla, University of Cantabria, Santander, Spain (Dr. Fariñas)
Microbiology, University Hospital Marqués de Valdecilla, University of Cantabria, Santander, Spain (Dr. Salesa)
Neurosurgery, University Hospital Marqués de Valdecilla, University of Cantabria, Santander, Spain (Dr. Vázquez).

We report the treatment of cerebral aspergillosis with amphotericin B, flucytosine, surgery, and liposomal amphotericin B (L-AmB) after a liver transplant. The patient died 2 months after cessation of antifungal therapy, as a consequence of multiple-system organ failure. The only relevant postmortem finding in the brain was a small, encapsulated abscess containing hyphae. This case indicates that L-AmB is an effective alternative drug for cerebral aspergillosis.

Address correspondence and reprint requests to Dr. José M. Polo, Servicio de Neurología, Hospital Universitario Marqués de Valdecilla, 39008 Santander, Spain.

Received December 3, 1991. Accepted for publication in final form February 6, 1992.

This article has been cited by other articles:

				M. D. Johnson, C. MacDougall, L. Ostrosky-Zeichner, J. R. Perfect, and J. H. Rex Combination Antifungal Therapy Antimicrob. Agents Chemother., March 1, 2004; 48(3): 693 - 715. [Full Text] [PDF]

				R. Selby, C. B. Ramirez, R. Singh, I. Kleopoulos, S. Kusne, T. E. Starzl, and J. Fung Brain Abscess in Solid Organ Transplant Recipients Receiving Cyclosporine-Based Immunosuppression Arch Surg, March 1, 1997; 132(3): 304 - 310. [Abstract] [PDF]