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Unité INSERM 330, Université de Bordeaux II, Hôpital Pellegrin, Bordeaux, France (Drs. Dartigues, Barberger-Gateau, and Commenges; and M. Gagnon and L. Letenneur)
Clinique Neurologique, Hôpital Pellegrin, Bordeaux, France (Drs. Dartigues and Orgogozo)
Service de Réeéeducation Fonctionnelle Neurologique (Dr. Mazaux), Hôpital Pellegrin, Bordeaux, France.
Using data obtained during the baseline screening of the PAQUID cohort, an epidemiologic study on brain aging conducted in the Bordeaux area of France, we studied the relationship between lifetime occupation and memory performance in visual recognition (Benton Visual Retention Test; BVRT) and verbal induced recall (Wechsler Paired Associates Test; WPAT) in 2,720 elderly community residents. Occupational category was strongly correlated with poor memory performance for both the BVRT and the WPAT. Independent of the educational level, the risk of having poor memory performance was two to three times greater for farmers, domestic service employees, and blue-collar workers than for professionals/managerials. Occupational category should be taken into account in future cross-national studies on brain aging.
Supported by Fondation de France, Sandoz Laboratories, Axa Insurance Group, Conseil Général de la Gironde, Conseil Général de la Dordogne, Ministère de la Recherche et de la Technologie, Caisse Nationale d'Assurance Maladie, Caisse Primaire d'Assurance Maladie de Dordogne, Mutualité Sociale Agricole de Gironde et Dordogne, Conseil Régional d'Aquitaine, Société Pechiney, 2010 Media, Caisse de Retraite Interentreprise, Capimmec, Institut du Cerveau, and Direction Régionale des Affaires Sanitaires et Sociales d'Aquitaine.
Received November 20, 1991. Accepted for publication in final form February 20,1992.
Address correspondence and reprint requests to Dr. Jean-François Dartigues, INSERM U. 330, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France.
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