Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mavra, M.
Right arrow Articles by Thompson, E. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mavra, M.
Right arrow Articles by Thompson, E. J.
NEUROLOGY 1992;42:1244
© 1992 American Academy of Neurology

Oligoclonal immunoglobulin D in the cerebrospinal fluid of neurologic patients

Milica Mavra, MD, PhD, Richard Luxton, MSc, Geoffrey Keir, MSc, PhD and Edward J. Thompson, MD, PhD

Department of Special Chemical Pathology, The National Hospital for Neurology and Neurosurgery, London, United Kingdom.

Oligoclonal immunoglobulin D (IgD) bands were observed in 20 of 110 CSF samples investigated by our method for isoelectric focusing (IEF) of IgD in unconcentrated CSF. These were mostly from demyelinating disorders, viral CNS infections, and CNS tumors. The patterns of expression of IgD were similar to that of IgG, except in cases with tumors where oligoclonal IgD may occur independently of IgG. The study shows for the first time the presence of oligoclonal IgD in CSF from neurologic patients.

Address correspondence and reprint requests to Dr. Edward J. Thompson, Department of Special Chemical Pathology, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1 3BG, United Kingdom.

Received August 2, 1991. Accepted for publication in final form November 15, 1991.




This article has been cited by other articles:


Home page
 CVIHome page
A. O. Vladutiu
Immunoglobulin D: Properties, Measurement, and Clinical Relevance
Clin. Vaccine Immunol., March 1, 2000; 7(2): 131 - 140.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by AAN Enterprises, Inc.