HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Nuwer, M. R. Articles by McArthur, J. C. Search for Related Content PubMed PubMed Citation Articles by Nuwer, M. R. Articles by McArthur, J. C.

Asymptomatic HIV infection does not cause EEG abnormalities

Results from the Multicenter AIDS Cohort Study (MACS)^*

Department of Neurology, University of California at Los Angeles, CA (Dr. Nuwer)
Medical Center Clinical Neurophysiology Department, University of California at Los Angeles, CA (Drs. Nuwer and Packwood and L.G. Carlson)
Neuropsychiatrie Institute, University of California at Los Angeles, CA (Drs. Miller and Satz)
School of Public Health, University of California at Los Angeles, CA (Dr. Visscher)
Department of Neurology Johns Hopkins University, Baltimore, MD. (Drs. Niedermeyer, Jankel, and McArthur)

We conducted EEG testing in 200 asymptomatic homosexual men, half of whom were HIV seropositive. We chose to include half of the subjects because they were rated as impaired on a neuropsychological screening test. We used both traditional visual EEG interpretation and quantitative EEG analysis. Abnormal EEGs and borderline degrees of EEG slowing occurred in 32% of these men. These EEG changes were not related to HIV serostatus. EEG changes did correlate with the impaired neuropsychological test performance. Clinicians faced with abnormal EEG results or borderline EEG slowing in an asymptomatic HIV-seropositive patient should not attribute the EEG change to effects of the serostatus itself but should look for other causes.

Address correspondence and reprint requests to Dr. Marc R. Nuwer, UCLA Department of Neurology, Reed Neurological Research Center, 710 Westwood Plaza, Los Angeles, CA 90024-6987.

^* The Multicenter AIDS Cohort Study Neuropsychologic Working Group consists of the following investigators in addition to the cited authors: Baltimore, The Johns Hopkins Medical Institutions—Julie H. McArthur, RN, BSN; Ola A. Seines, PhD; Lisa Jacobson, MS; Alvaro Munoz, PhD; and Alfred Saah, MD, MPH; Chicago, Howard Brown Memorial Clinic-Northwestern University Medical School—Joan S. Chmiel, PhD; Bruce A. Cohen, MD; Jerry Wesch, PhD; and John P. Phair, MD; Los Angeles, University of California at Los Angeles Schools of Public Health and Medicine—Hal Morgenstern, PhD; Jan Dudley, MPH; Elyse Singer, MD; Wilfred van Gorp, PhD; and Roger Detels, MD, MS; Pittsburgh, University of Pittsburgh Graduate School of Public Health and School of Medicine—Charles R. Rinaldo, Jr., PhD; and James T. Becker, PhD.

Supported by National Institutes of Health contracts AI 32520, AI 72631, AI 72634, AI 32535, the OP GCRC 5MO1 RR00722, and by UCLA AIDS Clinical Research Center grant 90R CC86LA.

Received October 4, 1991. Accepted for publication in final form November 26, 1991.

This article has been cited by other articles:

				S. Jenssen Electroencephalogram in the dementia workup American Journal of Alzheimer's Disease and Other Dementias, May 1, 2005; 20(3): 159 - 166. [Abstract] [PDF]

				M J G Harrison, S P Newman, M A Hall-Craggs, C J Fowler, R Miller, B E Kendall, M Paley, I Wilkinson, B Sweeney, S Lunn, et al. Evidence of CNS impairment in HIV infection: clinical, neuropsychological, EEG, and MRI/MRS study J. Neurol. Neurosurg. Psychiatry, September 1, 1998; 65(3): 301 - 307. [Abstract] [Full Text]