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Neurology Division, St. Elizabeth's Hospital, and the Neurological/Neurosurgical Intensive Care Unit, Massachusetts General Hospital, Boston, MA.
We present the hemodynamic and autonomie features of recurrent purely vasodepressor syncope episodes in a patient with left-sided malignant cervical adenopathy involving the carotid sinus. Extreme hypotension lasting 10 to 30 minutes, without change in heart rate, occurred spontaneously and 20 seconds after head-turning. The baseline respiratory sinus arrhythmia, heart rate response to standing and Valsalva's maneuver, and cold-induced blood pressure elevation were normal, indicating normal baroreceptor function between episodes. The episodes abated after 1 week of bedrest but reappeared within 1 day of discharge from the hospital. Syncope no longer occurred after intracranial section of the left glossopharyngeal nerve and upper rootlets of the left vagus. Autonomie testing remained normal postoperatively. A review of the literature indicates that purely vasodepressor syncope has been more common with left carotid sinus lesions.
Address correspondence and reprint requests to Dr. Jeffrey I. Frank, Assistant Professor, Stroke Program, Department of Neurology, Northwestern University Medical School, 233 E. Erie Street, Suite 500, Chicago, IL 60611.
Received June 14, 1991. Accepted for publication in final form November 8, 1991.
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