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Frequent involvement of the optic radiation in patients with acute isolated optic neuritis

From the National Hospital for Neurology and Neurosurgery (Drs Hornabrook, Miller, Newton, MacManus, du Boulay, and Halliday, and Prof McDonald) and Moorfields Eye Hospital (Prof McDonald), London, UK

Magnetic resonance imaging revealed asymptomatic lesions in white matter regions corresponding with the optic radiations in 20 of 28 patients (71%) with clinically isolated optic neuritis. In contrast to the findings with symptomatic lesions, there was no relationship between the latency of the visual evoked potential and the presence of these asymptomatic posterior visual pathway lesions.

Address correspondence and reprint requests to Professor W.I. McDonald, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK

Received January 15, 1991 Accepted for publication in final form June 10, 1991

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