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NEUROLOGY 1992;42:115
© 1992 American Academy of Neurology

Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham Study

D. L. Bachman, MD, P. A. Wolf, MD, R. Linn, PhD, J. E. Knoefel, MD, J. CobbS, MPH, A. Belanger, BS, R. B. D'Agostino, PhD and L. R. White, MD

From the Department of Neurology (Drs. Bachman, Wolf, Linn, and Knoefel), Boston University School of Medicine, Boston, MA; Department of Mathematics (J. Cobb, A. Belanger, and Dr. D'Agostino), Boston University, Boston, MA, and Epidemiology, Demography, and Biometry Program (Dr. White), National Institute on Aging, Bethesda, MD.

We determined the prevalence of dementia and probable senile dementia of the Alzheimer type (SDAT) for biennial Exam 17 of the Framingham cohort (1982/1983). The prevalence of dementia was 30.5/1,000 for men and 48.2/1,000 for women and increased with advancing age. Cases of probable SDAT constituted 55.6% of all dementia cases. The prevalence of SDAT was 11.7/1,000 for men and 30.1/1,000 for women and also increased with advancing age. Prevalence of dementia and orobable SDAT were greater for women than men. The fema1e:male ratio of prevalence for cohort members 75 years of age and older was 1.8 for all cases of dementia and 2.8 for cases of probable SDAT.

Address correspondence and reprint requests to Dr. Philip A. Wolf, Department of Neurology, Boston University School of Medicine, 80 East Concord Street B608, Boston, MA 02118.

Supported by National Institutes of Health grant 1R01-AG-08122-01 and contract N01-HC-38-038.

Received February 6, 1991. Accepted for publication in final form June 17, 1991




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