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NEUROLOGY 1990;40:581
© 1990 American Academy of Neurology

Immune studies in human immunodeficiency virus infection with myasthenia gravis

A case report

Avindra Nath, MD, Ronald H. Kerman, PhD, Irwin S. Novak, MD and Jerry S. Wolinsky, MD

Departments of Neurology (Drs. Nath, Novak, and Wolinsky), and Surgery (Dr. Kerman), The University of Texas Health Science Center at Houston, TX.

A patient with human immunodeficiency virus infection had cellular and humoral immune responses studied longitudinally from the onset of generalized myasthenia gravis. Progressive decline in CD4+, CD45R+ and CD4+, CDw29+ T-cells, cellular immune responses to alloantigen and mitogen stimulation, and acetylcholine receptor antibody titers were associated with clinical improvement of all myasthenic symptoms.

Address correspondence and reprint requests to Dr. Jerry S. Wolinsky, The University of Texas Health Science Center at Houston, PO Box 20708, Houston, TX 77225.

Received May 24, 1989. Accepted for publication in final form September 18, 1989.






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