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Department of Medicine (Neurology), Cedar Rapids Hospitals, Cedar Rapids, IA.
We report 2 patients with transient, focal, repetitive, stereo-typed episodes of neurologic deficits during treatment with interleukin-2. One patient had recurrent monocular blindness, while the 2nd had recurrent homonymous quadrantanopia. We suggest that these attacks are provoked by endothelial cell activation induced by interleukin-2.
Address correspondence and reprint requests to Dr. Erich W. Streib, Internists P.C., 115 Eighth Street NE, Cedar Rapids, IA 52401.
Supported in part by Teacher-Investigator Development Award K07 NS884 (Dr. Fisher) and ROI NS20989.
Received April 3, 1989. Accepted for publication in final form June 29, 1989.
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