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NEUROLOGY 1990;40:128
© 1990 American Academy of Neurology

Eight families with Joseph's disease in India

S. Jain, MD, DM and M. C. Maheshwari, MD

Department of Neurology, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India.

We report 8 additional cases of Joseph's disease (JD) from India and conclude (1) the most common pattern is type III, with few cases of types II and II-III; (b) type III JD in India has an earlier onset of symptoms (mean age at onset, 25.6 years) than the Azorean cases; and (3) a "pinched face" is a frequent minor clinical sign.

Address correspondence and reprint requests to Dr. Satish Jain, Department of Neurology, Neurosciences Centre, AIIMS, New Delhi-110029, India.

Received January 20, 1989. Accepted for publication in final form June 7, 1989.






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