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NEUROLOGY 1989;39:436
© 1989 American Academy of Neurology

Hypersensitivity to carbamazepine presenting with a leukemoid reaction, eosinophilia, erythroderma, and renal failure

K. Ray-Chaudhuri, MRCP(UK), I. F. Pye, MD, FRCP and M. Boggild, MB, ChB

Department of Neurology, Leicester Royal Infirmary, Leicester, UK.

We report a patient in whom hypersensitivity to carbamazepine presented with generalized erythroderma, a severe leukemoid reaction, eosinophilia, hyponatremia, and renal failure. This is the first report of such an unusual reaction to carbamazepine.

Address correspondence and reprint requests to Dr. K. Ray-Chaudhuri, Department of Neurology, Leicester Royal Infirmary, Leicester LEI SWW, United Kingdom.

Received August 1, 1988. Accepted for publication in final form September 26, 1988.




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