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NEUROLOGY 1989;39:430
© 1989 American Academy of Neurology

Reoperation for malignant astrocytoma

N. A. Vick, MD, I. S. Ciric, MD, T. W. Eller, MD, J. W. Cozzens, MD and A. Walsh, RN

Division of Neurology, Evanston Hospital and Northwestern University Medical School, Evanston, IL. (Dr. Vick and MB. Walsh)
Division of Neurosurgery, Evanston Hospital and Northwestern University Medical School, Evanston, IL. (Drs. Ciric, Eller, and Cozzens)

We evaluated 15 consecutive patients with malignant astrocytomas who were reoperated for functional status and survival. Their Karnovsky Performance Status (KPS) was not changed by surgery. None suffered perioperative death, wound infection, or complications. Patients with glioblastoma maintained KPS unchanged for a mean of 13 weeks (median, 10 weeks); with anaplastic astrocytoma, mean, 37.2 weeks (median, 24 weeks). Life spans were approximately twice that of non-reoperated historical controls. Reoperation for patients with recurrent malignant astrocytoma should be seriously considered when a gross total re-resection can be the goal in a patient whose tumor is in an accessible brain region.

Address correspondence and reprint requests to Dr. Vick, Division of Neurology, Evanston Hospital, 2650 Ridge Avenue, Evanston, IL 60201.

Supported by NIH grant P50 NS20023 and the W. Freeman Memorial Fund.

Received July 19, 1988. Accepted for publication in final form September 26, 1988.




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