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High-dose intravenous human immuno-globulin in chronic inflammatory demyelinating polyneuropathy

Department of Immunohaemotology, Otago Medical School, Dunedin, New Zealand. (Dr. Faed)
Department of Neurology, Otago Medical School, Dunedin, New Zealand. (Drs. Day, Pollock, Taylor, Nukada, and Hammond-Tooke)

We treated nine consecutive patients with chronic inflammatory demyelinating polyneuropathy (CIDP) with high-dose intravenous human immunoglobulin (HIG), and clinical recovery rapidly followed. Disability that had persisted for months or years was often reversed in days. There were no major adverse reactions to HIG infusions.

Address correspondence and reprint requests to Dr. Pollock, University of Otago Medical School, P.O. Box 913, Dunedin, New Zealand.

Received June 22, 1988. Accepted for publication in final form September 12, 1988.

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