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NEUROLOGY 1989;39:381
© 1989 American Academy of Neurology

Familial idiopathic striopallidodentate calcifications

E. Ellie, MD, J. Julien, MD and X. Ferrer, MD

Département de Neurologie, Hopital du Haut-Lévêque, Pessac, France.

We report a father and son with striopallidodentate calcifications. Metabolic studies excluded calcium/phosphorus metabolism disturbances and no specific etiology was found. The structure of the calcified areas differed, on magnetic resonance imaging, depending on location and, probably, age. There are nine families with similar clinical and radiologic backgrounds and no evident etiology in the literature. Transmission is most often autosomal dominant, and in contrast with physiologic senescent basal ganglia calcification, the prognosis appears to be poor.

Address correspondence and reprint requests to Dr. Julien, Département de Neurologie, Hopital du Haut-Lévêque, 33604 Pessac Cedex, France.

Received July 29, 1988. Accepted for publication in final form September 22, 1988.




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