| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
From the Departments of Neurology (Drs. Caplan, Baquis, Pessin, Adelman, DeWitt, and Ho) and Neuroradiology (Dr. Kwan), Tufts University School of Medicine, Boston, MA; and the Division of Neurology (Drs. D'Alton and Izukawa), Ottawa Civic Hospital, Ottawa, Ontario, Canada.
We describe four patients and review prior reports to clarify the clinical, radiographic, and pathologic findings of intracranial vertebral artery (VA) dissection. A 43-year-old man and a 33-year-old woman had chronic bilateral VA dissecting aneurysms. The man had multiple episodes of subarachnoid hemorrhage (SAH) and necropsy showed multiple dissections and defects in the internal elastica. The woman had many brainstem TIAs and strokes during 3 years. Two other patients had SAH and unilateral dissections. Intracranial VA dissection causes four overlapping syndromes: (1) brainstem infarcts are usually due to subintimal dissection extending into the basilar artery, affect younger patients, and often are single fatal events; (2) SAH is due to subadventitial or transmural dissection; (3) aneurysms cause mass effect on the brainstem and lower cranial nerves; and (4) chronic dissections due to connective tissue defects cause extensive bilateral aneurysms and repeated TIAs, small strokes, and SAH.
Address correspondence and reprint requests to Dr. Caplan, Department of Neurology, Tufts University School of Medicine, 260 Tremont Street, Boston, MA 02111.
Received June 9, 1987. Accepted for publication in final form October 30, 1987.
This article has been cited by other articles:
|
|
 |
|
  R. Dittrich, I. Nassenstein, R. Bachmann, D. Maintz, D. G. Nabavi, W. Heindel, G. Kuhlenbaumer, and E. B. Ringelstein Polyarterial clustered recurrence of cervical artery dissection seems to be the rule Neurology, July 10, 2007; 69(2): 180 - 186. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. M. Metso, A. J. Metso, J. Helenius, E. Haapaniemi, O. Salonen, M. Porras, J. Hernesniemi, M. Kaste, and T. Tatlisumak Prognosis and Safety of Anticoagulation in Intracranial Artery Dissections in Adults Stroke, June 1, 2007; 38(6): 1837 - 1842. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Leys and S. Debette Anticoagulation in Cerebral Ischemia Associated With Intracranial Artery Dissections Is Safe, but Is It Enough to Recommend It? Stroke, June 1, 2007; 38(6): 1720 - 1721. [Full Text] [PDF]
|
|
|
|
 |
|
 J. S. Lee, S. W. Yong, O. Y. Bang, Y. S. Shin, B. M. Kim, and S. Y. Kim Comparison of Spontaneous Intracranial Vertebral Artery Dissection With Large Artery Disease Arch Neurol, December 1, 2006; 63(12): 1738 - 1744. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. I. Savitz and L. R. Caplan Vertebrobasilar Disease N. Engl. J. Med., June 23, 2005; 352(25): 2618 - 2626. [Full Text] [PDF]
|
|
|
|
 |
|
 C.-J. Chen, Y.-C. Tseng, T.-H. Lee, H.-L. Hsu, and L.-C. See Multisection CT Angiography Compared with Catheter Angiography in Diagnosing Vertebral Artery Dissection AJNR Am. J. Neuroradiol., May 1, 2004; 25(5): 769 - 774. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Chaves, C. Estol, M. M. Esnaola, K. Gorson, M. O'Donoghue, L. D. de Witt, and L. R. Caplan Spontaneous Intracranial Internal Carotid Artery Dissection: Report of 10 Patients Arch Neurol, June 1, 2002; 59(6): 977 - 981. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. L. HARRIS, M. STOLL, G. T. JONES, M. A. GRANADOS, W. K. PORTEOUS, A. M. VAN RIJ, and H. J. JACOB Identification of two susceptibility loci for vascular fragility in the Brown Norway rat Physiol Genomics, August 28, 2001; 6(3): 183 - 189. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. J. Wityk Stroke in a Healthy 46-Year-Old Man JAMA, June 6, 2001; 285(21): 2757 - 2762. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. van Gijn and G. J. E. Rinkel Subarachnoid haemorrhage: diagnosis, causes and management Brain, February 1, 2001; 124(2): 249 - 278. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. H. Shin, D. C. Suh, C. G. Choi, and H. K. Lee Vertebral Artery Dissection: Spectrum of Imaging Findings with Emphasis on Angiography and Correlation with Clinical Presentation RadioGraphics, November 1, 2000; 20(6): 1687 - 1696. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Leclerc, C. Lucas, O. Godefroy, L. Nicol, A. Moretti, D. Leys, and J. P. Pruvo Preliminary Experience Using Contrast-Enhanced MR Angiography to Assess Vertebral Artery Structure for the Follow-up of Suspected Dissection AJNR Am. J. Neuroradiol., September 1, 1999; 20(8): 1482 - 1490. [Abstract] [Full Text]
|
|
|
|
|
|
A. J. Grau, T. Brandt, F. Buggle, E. Orberk, J. Mytilineos, E. Werle, C. Conradt, M. Krause, R. Winter, and W. Hacke Association of Cervical Artery Dissection With Recent Infection Arch Neurol, July 1, 1999; 56(7): 851 - 856. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Hosoya, M. Adachi, K. Yamaguchi, T. Haku, T. Kayama, and T. Kato Clinical and Neuroradiological Features of Intracranial Vertebrobasilar Artery Dissection Stroke, May 1, 1999; 30(5): 1083 - 1090. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J M de Bray, I Penisson-Besnier, F Dubas, and J Emile Extracranial and intracranial vertebrobasilar dissections: diagnosis and prognosis J. Neurol. Neurosurg. Psychiatry, July 1, 1997; 63(1): 46 - 51. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Culebras, C. S. Kase, J. C. Masdeu, A. J. Fox, R. N. Bryan, C. B. Grossman, D. H. Lee, H. P. Adams, W. Thies, and E. O. Members Practice Guidelines for the Use of Imaging in Transient Ischemic Attacks and Acute Stroke : A Report of the Stroke Council, American Heart Association Stroke, July 1, 1997; 28(7): 1480 - 1497. [Full Text]
|
|
|
|
|
|
Y. Yoshimoto and S. Wakai Unruptured Intracranial Vertebral Artery Dissection: Clinical Course and Serial Radiographic Imagings Stroke, February 1, 1997; 28(2): 370 - 374. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
