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From the Stroke Service and Department of Neurology (Drs. Gorelick and Hier), the Michael Reese Hospital and Medical Center, and the University of Illinois College of Medicine (Drs. Gorelick and Taber), Chicago, IL; the Tufts-New England Medical Center (Drs. Caplan and Pessin), Boston, MA; the School of Public Health Biometry Section (Dr. Langenberg), the University of Illinois at Chicago, and the Department of Diagnostic Radiology (Neuroradiology Section) (Dr. Patel), the Michael Reese Hospital and Medical Center, Chicago, IL.
We compared clinical and arteriographic features in 106 patients with symptomatic unilateral carotid territory occlusive disease to determine the frequency and distribution of occlusive arterial lesions in asymptomatic vessels. Among black patients who were predominantly from Chicago, young, and female, there were fewer transient ischemic attacks and myocardial infarcts, less claudication, and more asymptomatic lesions of the supraclinoid internal carotid artery, anterior cerebral artery stem, and the middle cerebral artery stem. Among white patients predominantly from New England, elderly, and male, there was more frequent and severe occlusive asymptomatic disease at extracranial carotid and vertebral artery sites. Knowledge of the distribution of asymptomatic lesions will help guide evaluation and treatment strategies for patients with occlusive cerebrovascular disease.
Address correspondence and reprint requests to Dr. Gorelick, Stroke Service, Department of Neurology, Michael Reese Hospital, 2900 Ellis Avenue, Chicago, IL 60616.
Supported in part by a Student Scholarship in Stroke to J. T., NIH Contract #N01-NS-2-2399, a grant from the AMOCO Foundation, and NIA Clinical Investigator Award 1-K08-AG-00350-01A1 to P.B.G.
Presented in part at the thirty-eighth annual meeting of the American Academy of Neurology, New Orleans, LA, April 1986.
Received August 11, 1987. Accepted for publication in final form October 13, 1987.
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