HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Sutherling, W. W. Articles by Barth, D. S. Search for Related Content PubMed PubMed Citation Articles by Sutherling, W. W. Articles by Barth, D. S.

The magnetic and electric fields agree with intracranial localizations of somatosensory cortex

Department of Neurology (Drs. Sutherling, Crandall, and Barth), Division of Neurosurgery (Drs. Crandall, Backer, and Levesque), and the Department of Psychology (Dr. Barth), University of California, Los Angeles, CA; and the Neurology Service and Neuropsychology Laboratory, Veterans Administration Hospital, West Haven, and the Yale University School of Medicine (Dr. Darcey), New Haven, CT.

We measured the magnetoencephalogram (MEG), electroencephalogram (EEG), and electrocorticogram (ECoG) after stimulation of contralateral median nerve in four patients with partial epilepsy evaluated for surgery. Quantitative localization estimates from equivalent source modeling were compared with locations of central fissure in hand sensorimotor area determined by cortical stimulations, intraoperative photographs, and examination after excision in frontal lobe. We also measured MEG and EEG in nine control subjects. MEG and EEG localizations were within 2.5 cm of the estimated location of central fissure in all 13 subjects. In the three patients who had complete mapping of all three fields, the average distance of localizations from central fissure was approximately 4 mm in both MEG and EEG, 3 mm in ECoG, and 3 mm in combined MEG and EEG. MEG was simpler than EEG, which was simpler than ECoG. MEG resolved ambiguities in both EEG and ECoG. The combination of the three fields added information about the spatiotemporal activity of somatosensory cortex. Localization of central fissure was essential to surgical treatment.

Address correspondence and reprint requests to Dr. Sutherling, Department of Neurology, UCLA School of Medicine, Reed Neurological Research Center, 710 Westwood Plaza, Los Angeles, CA 90024–1769.

Supported by the National Institute of Neurological and Communicative Disorders and Stroke, Epilepsy Branch, research grant NS20806. Dr. Sutherling is a recipient of a Teacher Investigator Development Award (NS00678) from the National Institute of Neurological and Communicative Disorders and Stroke and a Merritt-Putnam Fellowship from the Epilepsy Foundation of America.

Received February 8, 1988. Accepted for publication in final form April 29, 1988.

This article has been cited by other articles:

				A. Korvenoja, E. Kirveskari, H. J. Aronen, S. Avikainen, A. Brander, J. Huttunen, R. J. Ilmoniemi, J. E. Jaaskelainen, T. Kovala, J. P. Makela, et al. Sensorimotor Cortex Localization: Comparison of Magnetoencephalography, Functional MR Imaging, and Intraoperative Cortical Mapping Radiology, October 1, 2006; 241(1): 213 - 222. [Abstract] [Full Text] [PDF]

				K. Onoda, T. Kobayakawa, M. Ikeda, S. Saito, and A. Kida Laterality of Human Primary Gustatory Cortex Studied by MEG Chem Senses, October 1, 2005; 30(8): 657 - 666. [Abstract] [Full Text] [PDF]

				H. Nakahara, N. Nakasato, A. Kanno, S. Murayama, K. Hatanaka, H. Itoh, and T. Yoshimoto Somatosensory-evoked Fields for Gingiva, Lip, and Tongue Journal of Dental Research, April 1, 2004; 83(4): 307 - 311. [Abstract] [Full Text] [PDF]

				N. D. Schiff, U. Ribary, D. R. Moreno, B. Beattie, E. Kronberg, R. Blasberg, J. Giacino, C. McCagg, J. J. Fins, R. Llinas, et al. Residual cerebral activity and behavioural fragments can remain in the persistently vegetative brain Brain, June 1, 2002; 125(6): 1210 - 1234. [Abstract] [Full Text] [PDF]

				A. C. Papanicolaou, P. G. Simos, J. I. Breier, J. W. Wheless, P. Mancias, J. E. Baumgartner, W. W. Maggio, W. Gormley, J. E.C. Constantinou, and I. I. Butler Brain Plasticity for Sensory and Linguistic Functions: A Functional Imaging Study Using Magnetoencephalography With Children and Young Adults J Child Neurol, April 1, 2001; 16(4): 241 - 252. [Abstract] [PDF]

				N. Forss, M. Hietanen, O. Salonen, and R. Hari Modified activation of somatosensory cortical network in patients with right-hemisphere stroke Brain, October 1, 1999; 122(10): 1889 - 1899. [Abstract] [Full Text] [PDF]

				J. I. Breier, P. G. Simos, G. Zouridakis, J. W. Wheless, L. J. Willmore, J. E. C. Constantinou, W. W. Maggio, and A. C. Papanicolaou Language dominance determined by magnetic source imaging: A comparison with the Wada procedure Neurology, September 1, 1999; 53(5): 938 - 938. [Abstract] [Full Text]