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NEUROLOGY 1987;37:1534
© 1987 American Academy of Neurology

Herpes simplex encephalitis in third trimester of pregnancy

Successful outcome for mother and child

Graeme John Hankey, MBBS, Marion Ruth Bucens, FRCPA and John S.W. Chambers, MA, MS, FRCS, FRCOG, FAGO

Departments of Neurology (Dr. Hankey), and Gynecology and Obstetrics (Dr. Chambers), Royal Perth Hospital, and the State Health Laboratory Services (Dr. Bucens), Health Department of Western Australia, Perth, Western Australia.

A woman with herpes simplex encephalitis (HSE) in the third trimester of pregnancy is described. She was treated with acyclovir and recovered completely to deliver a normal child per vaginam at term. She had no evidence of genital or disseminated herpes virus infection. This paper illustrates that (1) the outcome of HSE in pregnancy can be favorable both for the mother and the offspring, (2) early diagnosis and use of acyclovir therapy is essential for successful outcome, and (3) the use of acyclovir in the third trimester of pregnancy was not harmful to the mother or fetus.

Address correspondence and reprint requests to Dr. Hankey, Department of Neurology, Royal Perth Hospital, Box X2213 G.P.O., Perth, Western Australia, 6001.

Received September 22, 1986. Accepted for publication in final form December 23, 1986.




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Obstet GynecolHome page
O. Dupuis, F. Audibert, H. Fernandez, and R. Frydman
HERPES SIMPLEX VIRUS ENCEPHALITIS IN PREGNANCY
Obstet. Gynecol., November 1, 1999; 94(5): 810 - 812.
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