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NEUROLOGY 1987;37:1525
© 1987 American Academy of Neurology

Effect of psychotropic medications on seizure control in patients with epilepsy

L. M. Ojemann, MD, C. Baugh-Bookman, BS and D. L. Dudley, MD

Epilepsy Center, Department of Neurological Surgery, School of Medicine, University of Washington, Seattle, WA.

Psychiatric problems are frequently encountered in patients with epilepsy. In an adult clinic population of 2,000 patients, 219 were identified as having been treated with psychotropic medication (PTM). Of these, 59 patients had adequate documentation of seizure frequency 2 months prior to and 2 months during treatment with PTMs. Contrary to many reports, most patients experienced better seizure control on PTM therapy. This demonstrates that most patients will not have an increased frequency of seizures when psychotropic medication is used in low to moderate doses and is introduced slowly.

Address correspondence and reprint requests to Dr. Ojemann, Regional Epilepsy Center ZA-50, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104.

Supported in part by NIH-NINCDS P50-NS-17111.

Received July 1, 1986. Accepted for publication in final form December 30, 1986.




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