Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sussman, N. M.
Right arrow Articles by Harner, R. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sussman, N. M.
Right arrow Articles by Harner, R. N.
NEUROLOGY 1987;37:350
© 1987 American Academy of Neurology

Magnetic resonance imaging after corpus callosotomy

N. M. Sussman, MD, M. Scanlon, MD, W. Garfinkle, MD, M. Callanan, MSN, M. J. O'Connor, MD and R. N. Harner, MD

Mid-Atlantic Regional Epilepsy Center (Dr. Sussman, Ms. Callanan, and Dr. Harner), the Medical College of Pennsylvania; the Department of Neurosurgery (Dr. O'Connor), Graduate Hospital; and the Department of Radiology (Drs. Scanlon and Garfinkle), Einstein Northern Hospital, Philadelphia, PA.

Magnetic resonance imaging (MRI) can visualize the extent of corpus callosotomy performed for medically intractable epilepsy not amenable to focal surgery. Five patients underwent complete callosotomy and one an anterior callosotomy, aged 19 to 24 years, 21 to 53 months (prior to scanning). T1 images showed complete absence of the callosal shadow in five cases and visualization of the genu and splenium in the sixth case. T2-weighted pulse sequence spinecho MRI showed intense image throughout the region of the entire callosum in the two cases with the longest postoperative course. The two middle cases showed intense T2 signal from the splenium, and the two latest showed no increase in T2 signal. We believe the increase in T2 signal in the transected callosum may represent an in vivo example of anisomorphic gliosis. T1 images demonstrate the anatomic extent of transection, while T2 images demonstrate the chemical and pathophysiologic sequence of transection. Thus, MRI is the imaging test of choice to evaluate callosotomy patients.

Address correspondence and reprint requests to Dr. Sussman, Mid-Atlantic Regional Epilepsy Center. MCP/EPPI, 3200 Henry Avenue, Philadelphia, PA 19129.

Received March 19, 1986. Accepted for publication May 14, 1986.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1987 by AAN Enterprises, Inc.