Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rajput, A. H.
Right arrow Articles by Kurland, L. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rajput, A. H.
Right arrow Articles by Kurland, L. T.
NEUROLOGY 1987;37:226
© 1987 American Academy of Neurology

A case-control study of smoking habits, dementia, and other illnesses in idiopathic Parkinson's disease

A. H. Rajput, FRCP(C), Kenneth P. Offord, MS, C. Mary Beard, RN, MPH and L. T. Kurland, MD, DrPH

Department of Clinical Neurological Sciences (Dr. Rajput). University of Saskatchewan, Saskatoon, Saskatchewan, Canada; and the Department of Medical Statistics and Epidemiology (Mr. Offord, Ms. Beard, and Dr. Kurland), Mayo Clinic, Rochester, MN.

From 1967 to 1979, 118 incident cases of idiopathic Parkinson's disease (IPD) and 236 age- and sex-matched controls from Rochester, MN, were identified. Medical records on patients and controls for 40 years preceding the diagnosis of IPD were reviewed. The relative risk (RR) for ever-smoked and IPD was not significantly different from unity (RR = 0.7, 95% confidence interval = 0.4 to 1.2). The mean age at diagnosis of IPD was significantly younger (p = 0.007) in the ever-smokers (68.8 years) compared with never-smokers (73.8 years), although this needs to be interpreted cautiously. It is concluded that smoking had no effect on the development of IPD. Within 5 years after the index date, a new diagnosis of dementia was made more often in cases than in controls (p = 0.01). Relative risk of IPD significantly increased when prior diagnosis of psychoneurosis and psychosomatic illness had been made.

Address correspondence and reprint requests to Dr. Rajput, Department of Clinical Neurological Sciences, University Hospital, Saskatoon, Saskatchewan S7N 0X0 Canada.

Supported in part by Grants AM-30582 and NS-17750 from the National Institutes of Health, Public Health Service, Bethesda, MD.

Received October 18, 1983. Accepted for publication June 6, 1986.




This article has been cited by other articles:


Home page
 NeurologyHome page
R. Inzelberg and J. Jankovic
Are Parkinson disease patients protected from some but not all cancers?
Neurology, October 9, 2007; 69(15): 1542 - 1550.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
J. E. Galvin, J. Pollack, and J. C. Morris
Clinical phenotype of Parkinson disease dementia.
Neurology, November 14, 2006; 67(9): 1605 - 1611.
[Abstract] [Full Text] [PDF]

Home page
 J PsychopharmacolHome page
K. A. Sacco, K. L. Bannon, and T. P. George
Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders
J Psychopharmacol, December 1, 2004; 18(4): 457 - 474.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
P. E. O'Suilleabhain, V. Sung, C. Hernandez, L. Lacritz, R. B. Dewey Jr, T. Bottiglieri, and R. Diaz-Arrastia
Elevated Plasma Homocysteine Level in Patients With Parkinson Disease: Motor, Affective, and Cognitive Associations
Arch Neurol, June 1, 2004; 61(6): 865 - 868.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
P. O'Suilleabhain and R. Diaz-Arrastia
Levodopa Elevates Homocysteine: Is This a Problem?
Arch Neurol, May 1, 2004; 61(5): 633 - 634.
[Full Text] [PDF]

Home page
 Arch NeurolHome page
H. Apaydin, J. E. Ahlskog, J. E. Parisi, B. F. Boeve, and D. W. Dickson
Parkinson Disease Neuropathology: Later-Developing Dementia and Loss of the Levodopa Response
Arch Neurol, January 1, 2002; 59(1): 102 - 112.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
M. D. Benedetti, J. H. Bower, D. M. Maraganore, S. K. McDonnell, B. J. Peterson, J. E. Ahlskog, D. J. Schaid, and W. A. Rocca
Smoking, alcohol, and coffee consumption preceding Parkinson's disease: A case-control study
Neurology, November 14, 2000; 55(9): 1350 - 1358.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
T. A. Hughes, H. F. Ross, S. Musa, S. Bhattacherjee, R. N. Nathan, R. H. S. Mindham, and E. G. S. Spokes
A 10-year study of the incidence of and factors predicting dementia in Parkinson's disease
Neurology, April 25, 2000; 54(8): 1596 - 1603.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M. A Hely, J. G L Morris, R. Traficante, W. G J Reid, D. J O'Sullivan, and P. M Williamson
The Sydney multicentre study of Parkinson's disease: progression and mortality at 10 years
J. Neurol. Neurosurg. Psychiatry, September 1, 1999; 67(3): 300 - 307.
[Abstract] [Full Text]

Home page
 NeurologyHome page
J. M. Gorell, B. A. Rybicki, C. C. Johnson, and E. L. Peterson
Smoking and Parkinson's disease: A dose-response relationship
Neurology, January 1, 1999; 52(1): 115 - 115.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
F. Mahieux, G. Fenelon, A. Flahault, M.-J. Manifacier, D. Michelet, and F. Boller
Neuropsychological prediction of dementia in Parkinson's disease
J. Neurol. Neurosurg. Psychiatry, February 1, 1998; 64(2): 178 - 183.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1987 by AAN Enterprises, Inc.