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Departments of Neuroradiology, and Medical Virology and Epidemiology of Virus Diseases, University of Tübingen, Tübingen, Germany.
The mortality rate of herpes simplex encephalitis (HSE) may be reduced by antiviral therapy, but early administration of the drug and therefore early diagnosis are essential. In our experience with four cases, MRI is the most sensitive noninvasive test in early diagnosis of HSE due to its high sensitivity to inflammatory increased brain water content, and it is superior to CT in localizing the pathognomonic lesions of the limbic system.
Address correspondence and reprint requests to Dr. Schroth, Universitaet Tübingen, Abt. f. Neuroradiologie, Osianderstrasse 22, D-74 Tübingen, Federal Republic of Germany.
Supported by Deutsche Forschungsgemeinschaft (DFG).
Received October 23, 1985. Accepted for publication May 20, 1986.
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R. R Edelman and S. Warach Magnetic Resonance Imaging- First of Two Parts N. Engl. J. Med., March 11, 1993; 328(10): 708 - 716. [Full Text]
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