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NEUROLOGY 1987;37:1849
© 1987 American Academy of Neurology

"Crack" cocaine-associated stroke

S. R. Levine, MD, J. M. Washington, MD, M. F. Jefferson, MD, S. N. Kieran, MD, M. Moen, MD, H. Feit, MD, PhD and K. M. A. Welch, MD

Center for Cerebrovascular Disease Research and Departments of Neurology and Emergency Medicine, Henry Ford Hospital, Detroit, MI.

We present three cases of "crack" cocaine-associated stroke, together with a review of cocaine-associated cerebrovascular complications. Unlike previously reported cases tentatively associating ischemic stroke with cocaine, our patients had no other potential causes for their strokes. Although the exact mechanism of cocaine-related stroke remains uncertain, both disordered neurogenic control of the cerebral circulation as well as systemic factors (ie, acute hypertension) may play a role.

Address correspondence and reprint requests to Dr. Levine, Department of Neurology, Henry Ford Hospital, 2977 West Grand Boulevard, Detroit, MI 48202.

Supported in part by an NIH grant #NS23393. Dr. Levine is currently a research fellow of the American Heart Association of Michigan.

Presented in part at the thirty-ninth annual meeting of the American Academy of Neurology, New York, NY, April 1987.

Received January 20, 1987. Accepted for publication in final form March 4, 1987.




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