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Departments of Neurology (Dr. Hershey, Mr. Greenough, and Mr. Jaffe) and Radiology (Dr. Modic), Case Western Reserve University School of Medicine and University Hospitals of Cleveland, OH.
Patients with vascular dementia show distinctive white matter lesions on MRI. We performed MRI on 34 patients with documented ischemic cerebrovascular disease to see whether demented and nondemented patients differ with respect to enlarged CSF spaces or white matter lesions. All eight demented patients had white matter lesions on MRI, just as did many borderline and nondemented patients. Enlargement of central CSF spaces was the only radiographic feature that was seen more commonly in demented than in nondemented patients with ischemic cerebrovascular disease.
Address correspondence and reprint requests to Dr. Hershey, Department of Neurology #127, Buffalo V.A. Medical Center, 3495 Bailey Ave., Buffalo, NY 14215.
Presented in part at the thirty-eighth annual meeting of the American Academy of Neurology, New Orleans, LA, April 1986.
Received February 5, 1986. Accepted for publication April 24, 1986.
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