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NEUROLOGY 1985;35:1055
© 1985 American Academy of Neurology

Fatal myoglobinuric renal failure in a patient with tardive dyskinesia

Arthur L. Lazarus, MD and Joseph U. Toglia, MD

Departments of Psychiatry (Dr. Lazarus), and Neurology (Dr. Toglia), Temple University School of Medicine, Philadelphia, PA.

A patient with severe tardive dyskinesia developed fatal myoglobinuric renal failure. Myoglobinuria has followed other forms of extreme muscular exertion, but has not been previously reported consequent to tardive dyskinesia. Antipsychotic medication should be used to treat severe tardive dyskinesia when alternative forms of therapy are ineffective and discontinuing therapy might otherwise lead to an exacerbation of symptoms with life-threatening complications.

Address correspondence and reprint requests to Dr. Lazarus, Department of Psychiatry, Temple University Health Sciences Center, 3401 North Broad Street, Philadelphia, PA 19140.

Accepted for publication November 8, 1984.






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