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Episodic cataitonia, hypertension, and tachycardia

Elevated plasma catecholaimines

Neurnlogy Service, March AFB, CA (Dr. Wheeler), and the Department of Medicine, University of Califomia at San Diego (Drs. Ziepler, Insel, and Motulsky), San Diego, CA.

We studied autonomic function in a 34-year-old woman who had episodes of catatonia, hypertension, and tachycardia. In one of these episodes, epinephrine and norepinephrine levels were extremely high. Catecholamine clearance was normal. Platelet alpha,-adrenergic receptors were normal in number and affinity. Results of the phenylephrine infusion test suggested that these episodes were due to central activation of the sympathetic nervous system.

Address correspondence and reprint requests to Dr. Wheeler. The Johnson Neurnlogical Clinic, PO Box 5708, High Point, NC 27262.

Accepted fur publication November 1, 1984

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