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NEUROLOGY 1985;35:911
© 1985 American Academy of Neurology

An acute syndrome with psychiatric symptoms and EEG abnormalities

Ivo Drury, MB, MRCP, Donald W. Klass, MD, Barbara F. Westmoreland, MD and Frank W. Sharbrough, MD

Section of Electroencephalography, Department of Neurology, Mayo Clinic and Mayo Foundation, Rochester, MN.

Four patients with abrupt onset of psychosis had prominent periodic EEG abnormalities with diffuse sharp waves. Other laboratory studies, including CSF and CT, were normal. The EEG abnormalities disappeared within 1 to 7 days. Clinical improvement was complete and commenced after the EEG showed improvement. The cause remains obscure, but it seems to be a transient organic disturbance of cerebral function that must be distinguished from primary psychiatric disorders.

Address correspondence and reprint requests to Dr. Klass, Mayo Clinic, 200 First Street SW, Rochester, MN 55905.

Dr. Drury is the recipient of the John F. Keenan Research Scholarship in Medicine from University College, Dublin, Ireland.

Accepted for publication October 14, 1984




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J. T. Hormes, E. E. Benarroch, M. Rodriguez, and D. W. Klass
Periodic Sharp Waves in Baclofen-Induced Encephalopathy
Arch Neurol, July 1, 1988; 45(7): 814 - 815.
[Abstract] [PDF]




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