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NEUROLOGY 1985;35:752
© 1985 American Academy of Neurology

Praziquantel in the treatment of neurocysticercosis

Long-term follow-up

Julio Sotelo, MD, Bertha Torres, MD, Francisco Rubio-Donnadieu, MD, Francisco Escobedo, MD and Jesus Rodriguez-Carbajal, MD

Research Division, Instituto Nacional de Neurologia y Neurocirugia, Mexico.

Thirty-five patients with active neurocysticercosis were treated with praziquantel and followed for 1 year after therapy. CT and CSF analysis showed that 91% of patients with parenchymal cysts improved, and 47% of patients with chronic arachnoiditis had remission. A single treatment with praziquantel for 2 weeks, administered in a daily dose of 50 mg/kg of body weight, was highly effective in parenchymal cysticercosis but less effective in meningeal cysticercosis. The benefits were sustained for at least 1 year.

Address correspondence and reprint requests to Dr. Sotelo, Research Division, Instituto Nacional de Neurologia y Neurocirugia, Av. Insurgentes Sur No. 3877, Mexico 22, DF 14400.

Supported by the Instituto Nacional de Neurologia y Neurocirugia de Mexico.

Accepted for publication September 12, 1984.




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