NEUROLOGY 1985;35:752
© 1985 American Academy of Neurology
Praziquantel in the treatment of neurocysticercosis
Long-term follow-up
Julio Sotelo, MD,
Bertha Torres, MD,
Francisco Rubio-Donnadieu, MD,
Francisco Escobedo, MD and
Jesus Rodriguez-Carbajal, MD
Research Division, Instituto Nacional de Neurologia y Neurocirugia, Mexico.
Thirty-five patients with active neurocysticercosis were treated with praziquantel and followed for 1 year after therapy. CT and CSF analysis showed that 91% of patients with parenchymal cysts improved, and 47% of patients with chronic arachnoiditis had remission. A single treatment with praziquantel for 2 weeks, administered in a daily dose of 50 mg/kg of body weight, was highly effective in parenchymal cysticercosis but less effective in meningeal cysticercosis. The benefits were sustained for at least 1 year.
Address correspondence and reprint requests to Dr. Sotelo, Research Division, Instituto Nacional de Neurologia y Neurocirugia, Av. Insurgentes Sur No. 3877, Mexico 22, DF 14400.
Supported by the Instituto Nacional de Neurologia y Neurocirugia de Mexico.
Accepted for publication September 12, 1984.
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