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Department of Neurology (Dr. Grotta and Ms. Vital), The University of Texas Medical School, and the Section of Neurology (Drs. Lemak, Gary, and Fields), The University of Texas M.D. Anderson Hospital and Tumor Institute.
Data from the Aspirin in Transient Ischemic Attack (AITIA) study, an ongoing study of two platelet antiaggregant drugs, and other published therapeutic trials were reviewed to determine whether the severity of stroke is reduced in patients taking platelet antiaggregants. Data from three of four studies suggest that strokes in treated patients are less severe than those in untreated patients. Further studies evaluating platelet antiaggregant therapy should include assessment of the severity as well as the incidence of stroke.
Address correspondence and reprint requests to Dr. Grotta, The University of Texas Medical School at Houston, Department of Neurology, PO Box 20708, Houston, TX 77030.
The AITIA study was supported by NHLBI grant #HL-14340-03.
Accepted for publication September 27, 1984.
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