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NEUROLOGY 1985;35:560
© 1985 American Academy of Neurology

Cytomegalovirus meningoencephalitis in a homosexual man with Kaposi's sarcoma

Isolation of CMV from CSF cells

R. H. Edwards, R. Messing and Robert R. McKendall

University of California and Veterans Administration Medical Center, San Francisco, CA.

A 36-year-old homosexual man developed a lymphocytic meningoencephalitis, lymphadenopathy, decreased helper/suppressor ratio in peripheral blood, and Kaposi's sarcoma. After repetitive evaluations for bacterial and fungal agents were negative, viral cultures were positive for cytomegalovirus. Virus was isolated only from CSF cells obtained from a large volume of fresh CSF. We present this case to document the association of CMV meningoencephalitis and acquired immunodeficiency syndrome (AIDS), and to emphasize that aggressive attempts to isolate CMV from CSF cells may be warranted in undiagnosed meningoencephalitis in patients at risk for AIDS.

Address correspondence and reprint requests to Dr. McKendall, Department of Neurology, University of Texas Medical Branch, Galveston, TX 77550.

Supported by research funds of VA Research and the Kroc Foundation.

Accepted for publication August 6, 1984.







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