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NEUROLOGY 1985;35:493
© 1985 American Academy of Neurology

Perimesencephalic hemorrhage

A nonaneurysmal and benign form of subarachnoid hemorrhage

J. van Gijn, K. J. van Dongen, M. Vermeulen and A. Hijdra

Department of Neuro1ogy (Dr. van Gijn). State university of Utrecht, and the Departments of Radiology (Dr. van Dongen) and Neurology (Drs. van Gijn. Vermeulen, and Hijdra), University Hospital (Dijkzigt), Rotterdam, The Netherlands.

We studied 28 patients with subarachnoid hemorrhage and normal angiograms. On early CT (within 5 days) in 13 cases, blood was seen mainly or only in the cisterns around the midbrain. This pattern of hemorrhage was found in only 1 of 92 patients with a ruptured aneurysm. None of the unexplained perimesencephalic hemorrhages was associated with intracerebral hematoma or intraventricular hemorrhage. The clinical features also differed from those of aneurysmal hemorrhage; loss of consciousness was rare, and after 3 months, all 13 patients had returned to normal life. The cause of this benign disorder remains elusive, but a venous or capillary source seems likely.

Address correspondence and reprint requests to Dr. van Gijn, Department of Neurology, State University of Utrecht. PO Box 16250, 3500 CG Utrecht. The Netherlands.

Accepted for publication August 10, 1984.




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