Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mayeux, R.
Right arrow Articles by Spanton, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mayeux, R.
Right arrow Articles by Spanton, S.
NEUROLOGY 1985;35:453
© 1985 American Academy of Neurology

Heterogeneity in dementia of the Alzheimer type

Evidence of subgroups

Richard Mayeux, MD, Yaakov Stern, PhD and Susan Spanton

Department of Neurology, Columbia University, College of Physicians and Surgeons, and the Presbyterian Hospital in the City of New York

We reviewed records of 121 consecutive patients with dementia of the Alzheimer type. Patients with myoclonus or extrapyramidal signs had greater intellectual decline and functional impairment in daily activities. Among patients studied over 4 years, there were four groups: benign—little to no progression; myoclonic—severe intellectual decline and frequent mutism after younger onset; extrapyramidal—severe intellectual and functional decline and frequent psychotic symptoms; typical—a gradual progression of intellectual and functional decline, but without other distinguishing features. Except for the group with myoclonus, no subgroup was segregated by age at onset or other demographic variables. This study suggests that dementia of the Alzheimer type is heterogeneous, and that certain clinical manifestations may be useful in predicting outcome.

Address correspondence and reprint requests to Dr. Mayeux, 710 West 168th Street, Neurological Institute. New York. NY 10032.

Supported in part by the Charles S. Robertson Memorial Gift for Alzheimer's Disease from the Banbury Fund and a federal grant (AG 02802) to Dr. Mayeux. Data were stored and analyzed on a CLINFO system (NIH RK00645).

Presented in part at the thirty-sixth annual meeting of the American Academy of Neuroloky, Boston. MA, April 1984.




This article has been cited by other articles:


Home page
 Arch NeurolHome page
N. Scarmeas, L. S. Honig, H. Choi, J. Cantero, J. Brandt, D. Blacker, M. Albert, J. C. Amatniek, K. Marder, K. Bell, et al.
Seizures in Alzheimer Disease: Who, When, and How Common?
Arch Neurol, August 1, 2009; 66(8): 992 - 997.
[Abstract] [Full Text] [PDF]

Home page
 AM J ALZHEIMERS DIS OTHER DEMENHome page
E. A. Licht, A. M. McMurtray, R. E. Saul, and M. F. Mendez
Cognitive Differences between Early- and Late-Onset Alzheimer's Disease
American Journal of Alzheimer's Disease and Other Dementias, July 1, 2007; 22(3): 218 - 222.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
N. Scarmeas, J. Brandt, M. Albert, G. Hadjigeorgiou, A. Papadimitriou, B. Dubois, M. Sarazin, D. Devanand, L. Honig, K. Marder, et al.
Delusions and Hallucinations Are Associated With Worse Outcome in Alzheimer Disease
Arch Neurol, October 1, 2005; 62(10): 1601 - 1608.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
H. H. Feldman and M. Woodward
The staging and assessment of moderate to severe Alzheimer disease
Neurology, September 27, 2005; 65(6_suppl_3): S10 - S17.
[Abstract] [Full Text]

Home page
 NeurologyHome page
T. Edwards-Lee, J. M. Ringman, J. Chung, J. Werner, A. Morgan, P. St. G. Hyslop, P. Thompson, R. Dutton, A. Mlikotic, E. Rogaeva, et al.
An African American family with early-onset Alzheimer disease and an APP (T714I) mutation
Neurology, January 25, 2005; 64(2): 377 - 379.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. M. Heckmann, W.-C. Low, C. de Villiers, S. Rutherfoord, A. Vorster, H. Rao, C. M. Morris, R. S. Ramesar, and R. N. Kalaria
Novel presenilin 1 mutation with profound neurofibrillary pathology in an indigenous Southern African family with early-onset Alzheimer's disease
Brain, January 1, 2004; 127(1): 133 - 142.
[Abstract] [Full Text] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
J. Cohen-Mansfield
Nonpharmacologic Interventions for Psychotic Symptoms in Dementia
J Geriatr Psychiatry Neurol, December 1, 2003; 16(4): 219 - 224.
[Abstract] [PDF]

Home page
 NeurologyHome page
M. P. Caligiuri, G. Peavy, D. P. Salmon, D. R. Galasko, and L. J. Thal
Neuromotor abnormalities and risk for psychosis in Alzheimer's disease
Neurology, October 14, 2003; 61(7): 954 - 958.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
A. M. Brickman, A. Riba, K. Bell, K. Marder, M. Albert, J. Brandt, and Y. Stern
Longitudinal Assessment of Patient Dependence in Alzheimer Disease
Arch Neurol, August 1, 2002; 59(8): 1304 - 1308.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
J. C. Janssen, E. K. Warrington, H. R. Morris, P. Lantos, J. Brown, T. Revesz, N. Wood, M. N. Khan, L. Cipolotti, N. C. Fox, et al.
Clinical features of frontotemporal dementia due to the intronic tau 10+16 mutation
Neurology, April 23, 2002; 58(8): 1161 - 1168.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
N. Scarmeas, J. Brandt, M. Albert, D. P. Devanand, K. Marder, K. Bell, A. Ciappa, B. Tycko, and Y. Stern
Association between the APOE genotype and psychopathologic symptoms in Alzheimer's disease
Neurology, April 23, 2002; 58(8): 1182 - 1188.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
J. A. Schneider, J. L. Bienias, D. W. Gilley, D. E. Kvarnberg, E. J. Mufson, and D. A. Bennett
Improved Detection of Substantia Nigra Pathology in Alzheimer's Disease
J. Histochem. Cytochem., January 1, 2002; 50(1): 99 - 106.
[Abstract] [Full Text] [PDF]

Home page
 AM J ALZHEIMERS DIS OTHER DEMENHome page
N. Nagaratnam, G. Cheuk, and K. Nagaratnam
Slowly progressive aphasia with striatal involvement
American Journal of Alzheimer's Disease and Other Dementias, January 1, 2002; 17(1): 18 - 22.
[Abstract] [PDF]

Home page
 AM J ALZHEIMERS DIS OTHER DEMENHome page
M. Tsolaki, K. Kokarida, V. Iakovidou, E. Stilopoulos, J. Meimaris, and A. Kazis
Extrapyramidal symptoms and signs in Alzheimer's disease: Pravalence and correlation with the first symptom
American Journal of Alzheimer's Disease and Other Dementias, September 1, 2001; 16(5): 268 - 278.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
D. Mungas, B. R. Reed, W. G. Ellis, and W. J. Jagust
The Effects of Age on Rate of Progression of Alzheimer Disease and Dementia With Associated Cerebrovascular Disease
Arch Neurol, August 1, 2001; 58(8): 1243 - 1247.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
J. C. Janssen, P. L. Lantos, N. C. Fox, R. J. Harvey, J. Beck, A. Dickinson, T. A. Campbell, J. Collinge, D. P. Hanger, L. Cipolotti, et al.
Autopsy-Confirmed Familial Early-Onset Alzheimer Disease Caused by the L153V Presenilin 1 Mutation
Arch Neurol, June 1, 2001; 58(6): 953 - 958.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M A L. Ralph, J Powell, D Howard, A B Whitworth, P Garrard, and J R Hodges
Semantic memory is impaired in both dementia with Lewy bodies and dementia of Alzheimer's type: a comparative neuropsychological study and literature review
J. Neurol. Neurosurg. Psychiatry, February 1, 2001; 70(2): 149 - 156.
[Abstract] [Full Text] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
L. Demers, M. Oremus, A. Perrault, N. Champoux, and C. Wolfson
Review of Outcome Measurement Instruments in Alzheimer's Disease Drug Trials: Psychometric Properties of Functional and Quality of Life Scales
J Geriatr Psychiatry Neurol, December 1, 2000; 13(4): 170 - 180.
[Abstract] [PDF]

Home page
 BrainHome page
A. B. Singleton, R. Hall, C. G. Ballard, R. H. Perry, J. H. Xuereb, D. C. Rubinsztein, C. Tysoe, P. Matthews, B. Cordell, S. Kumar-Singh, et al.
Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation
Brain, December 1, 2000; 123(12): 2467 - 2474.
[Abstract] [Full Text] [PDF]

Home page
 Arch Gen PsychiatryHome page
N. B. Farber, E. H. Rubin, J. W. Newcomer, D. A. Kinscherf, J. P. Miller, J. C. Morris, J. W. Olney, and D. W. McKeel Jr
Increased Neocortical Neurofibrillary Tangle Density in Subjects With Alzheimer Disease and Psychosis
Arch Gen Psychiatry, December 1, 2000; 57(12): 1165 - 1173.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
R. S. Wilson, D. A. Bennett, D. W. Gilley, L. A. Beckett, J. A. Schneider, and D. A. Evans
Progression of Parkinsonism and Loss of Cognitive Function in Alzheimer Disease
Arch Neurol, June 1, 2000; 57(6): 855 - 860.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. C. Janssen, M. Hall, N. C. Fox, R. J. Harvey, J. Beck, A. Dickinson, T. Campbell, J. Collinge, P. L. Lantos, L. Cipolotti, et al.
Alzheimer's disease due to an intronic presenilin-1 (PSEN1 intron 4) mutation: A clinicopathological study
Brain, May 1, 2000; 123(5): 894 - 907.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
R. S. Wilson, D. A. Bennett, D. W. Gilley, L. A. Beckett, J. A. Schneider, and D. A. Evans
Progression of parkinsonian signs in Alzheimer's disease
Neurology, March 28, 2000; 54(6): 1284 - 1289.
[Abstract] [Full Text] [PDF]

Home page
 J. Neuropsychiatry Clin. Neurosi.Home page
M. P. Caligiuri and G. Peavy
An Instrumental Study of the Relationship Between Extrapyramidal Signs and Psychosis in Alzheimer's Disease
J Neuropsychiatry Clin Neurosci, February 1, 2000; 12(1): 34 - 39.
[Abstract] [Full Text]

Home page
 BrainHome page
S. Poser, B. Mollenhauer, A. Krau{beta}, I. Zerr, B. J. Steinhoff, A. Schroeter, M. Finkenstaedt, W. J. Schulz-Schaeffer, H. A. Kretzschmar, and K. Felgenhauer
How to improve the clinical diagnosis of Creutzfeldt-Jakob disease
Brain, December 1, 1999; 122(12): 2345 - 2351.
[Abstract] [Full Text] [PDF]

Home page
 J. Neuropsychiatry Clin. Neurosi.Home page
V. Rao and C. G. Lyketsos
Delusions in Alzheimer's Disease: A Review
J Neuropsychiatry Clin Neurosci, November 1, 1998; 10(4): 373 - 382.
[Abstract] [Full Text]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M Lehtovirta, J Kuikka, S Helisalmi, P Hartikainen, A Mannermaa, M Ryynanen, P S. Riekkinen, and H Soininen
Longitudinal SPECT study in Alzheimer's disease: relation to apolipoprotein E polymorphism
J. Neurol. Neurosurg. Psychiatry, June 1, 1998; 64(6): 742 - 746.
[Abstract] [Full Text] [PDF]

Home page
 J. Neuropsychiatry Clin. Neurosi.Home page
R. A. Sweet, M. Akil, B. H. Mulsant, R. Ulrich, R. E. Pasternak, and G. S. Zubenko
Determinants of SPontaneous Extrapyramidal Symptoms in Elderly Psychiatric Inpatients Diagnosed With Alzheimer's Disease, Major Depressive Disorder, or Psychotic Disorders
J Neuropsychiatry Clin Neurosci, February 1, 1998; 10(1): 68 - 77.
[Abstract] [Full Text]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
R. J Harvey, D. Ellison, J. Hardy, M. Hutton, P. K Roques, J. Collinge, N. C Fox, and M. N Rossor
Chromosome 14 familial Alzheimer's disease: the clinical and neuropathological characteristics of a family with a leucineright-arrowserine (L250S) substitution at codon 250 of the presenilin 1 gene
J. Neurol. Neurosurg. Psychiatry, January 1, 1998; 64(1): 44 - 49.
[Abstract] [Full Text]

Home page
 Arch NeurolHome page
O. L. Lopez, S. R. Wisnieski, J. T. Becker, F. Boiler, and S. T. DeKosky
Extrapyramidal Signs in Patients With Probable Alzheimer Disease
Arch Neurol, August 1, 1997; 54(8): 969 - 975.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
B. M. French, M. R. W. Dawson, and A. R. Dobbs
Classification and Staging of Dementia of the Alzheimer Type: A Comparison Between Neural Networks and Linear Discriminant Analysis
Arch Neurol, August 1, 1997; 54(8): 1001 - 1009.
[Abstract] [PDF]

Home page
 BMJHome page
R. McShane, J. Keene, K. Gedling, C. Fairburn, R. Jacoby, and T. Hope
Do neuroleptic drugs hasten cognitive decline in dementia? Prospective study with necropsy follow up
BMJ, January 25, 1997; 314(7076): 266 - 266.
[Abstract] [Full Text]

Home page
 Arch NeurolHome page
G. D. Forno, D. X. Rasmusson, J. Brandt, K. A. Carson, R. Brookmeyer, J. Troncoso, and C. H. Kawas
Apolipoprotein E Genotype and Rate of Decline in Probable Alzheimer's Disease
Arch Neurol, April 1, 1996; 53(4): 345 - 350.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
L. A. Klatka, R. B. Schiffer, J. M. Powers, and A. M. Kazee
Incorrect Diagnosis of Alzheimer's Disease: A Clinicopathologic Study
Arch Neurol, January 1, 1996; 53(1): 35 - 42.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
D.P. Devanand and S. R. Levy
Neuroleptic Treatment of Agitation and Psychosis in Dementia
J Geriatr Psychiatry Neurol, October 1, 1995; 8(1): S18 - S27.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
D. J. Knesper
The Depressions of Alzheimer's Disease: Sorting, Pharmacotherapy, and Clinical Advice
J Geriatr Psychiatry Neurol, October 1, 1995; 8(1): S40 - S51.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
L. A. Farrer, L. A. Cupples, C. M. van Duijn, L. Connor-Lacke, D. K. Kiely, and J. H. Growdon
Rate of Progression of Alzheimer's Disease Is Associated With Genetic Risk
Arch Neurol, September 1, 1995; 52(9): 918 - 923.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
M. B. Snowden, J. D. Bowen, J. Hughes, and E. B. Larson
Study of Alzheimer's Dementia Patients with Parkinsonian Features
J Geriatr Psychiatry Neurol, July 1, 1995; 8(3): 154 - 158.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
K. Marder, M.-X. Tang, L. Cote, Y. Stern, and R. Mayeux
The Frequency and Associated Risk Factors for Dementia in Patients With Parkinson's Disease
Arch Neurol, July 1, 1995; 52(7): 695 - 701.
[Abstract] [PDF]

Home page
 J PsychopharmacolHome page
N.H.P. Allen and A. Burns
The treatment of Alzheimer's disease
J Psychopharmacol, January 1, 1995; 9(1): 43 - 56.
[PDF]

Home page
 Arch NeurolHome page
K. Axelman, H. Basun, B. Winblad, and L. Lannfelt
A Large Swedish Family With Alzheimer's Disease With a Codon 670/671 Amyloid Precursor Protein Mutation: A Clinical and Genealogical Investigation
Arch Neurol, December 1, 1994; 51(12): 1193 - 1197.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
L. Bracco, R. Gallato, F. Grigoletto, A. Lippi, V. Lepore, G. Bino, M. P. Lazzaro, F. Carella, T. Piccolo, C. Pozzilli, et al.
Factors Affecting Course and Survival in Alzheimer's Disease: A 9-Year Longitudinal Study
Arch Neurol, December 1, 1994; 51(12): 1213 - 1219.
[Abstract] [PDF]

Home page
 Clin RehabilHome page
V. Pomeroy
Immobility and severe dementia: when is physiotherapy treatment appropriate?
Clinical Rehabilitation, August 1, 1994; 8(3): 226 - 232.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
H. C. Chui, S. A. Lyness, E. Sobel, and L. S. Schneider
Extrapyramidal Signs and Psychiatric Symptoms Predict Faster Cognitive Decline in Alzheimer's Disease
Arch Neurol, July 1, 1994; 51(7): 676 - 681.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
J. T. Becker, F. Boiler, O. L. Lopez, J. Saxton, K. L. McGonigle, and Alzheimer Research Program
The Natural History of Alzheimer's Disease: Description of Study Cohort and Accuracy of Diagnosis
Arch Neurol, June 1, 1994; 51(6): 585 - 594.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
J. L. Mack and M. B. Patterson
The Evaluation of Behavioral Disturbances in Alzheimer's Disease: The Utility of Three Rating Scales
J Geriatr Psychiatry Neurol, April 1, 1994; 7(2): 99 - 115.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
M. Panisset, M. Roudier, J. Saxton, and F. Boiler
Severe Impairment Battery: A Neuropsychological Test for Severely Demented Patients
Arch Neurol, January 1, 1994; 51(1): 41 - 45.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
C. G. Benesch, K. D. McDaniel, C. Cox, and R. W. Hamill
End-Stage Alzheimer's Disease: Glasgow Coma Scale and the Neurologic Examination
Arch Neurol, December 1, 1993; 50(12): 1309 - 1315.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
L. D. McDaniel, T. Lukovits, and K. D. McDaniel
Alzheimer's Disease: The Problem of Incorrect Clinical Diagnosis
J Geriatr Psychiatry Neurol, October 1, 1993; 6(4): 230 - 234.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
E. H. Franssen, A. Kluger, C. L. Torossian, and B. Reisberg
The Neurologic Syndrome of Severe Alzheimer's Disease: Relationship to Functional Decline
Arch Neurol, October 1, 1993; 50(10): 1029 - 1039.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
B. H. Price, H. Gurvit, S. Weintraub, C. Geula, E. Leimkuhler, and M. Mesulam
Neuropsychological Patterns and Language Deficits in 20 Consecutive Cases of Autopsy-Confirmed Alzheimer's Disease
Arch Neurol, September 1, 1993; 50(9): 931 - 937.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
I. M. Zervas, J. M. Fliesser, M. Woznicki, and G. L. Fricchione
Presbyophrenia: A Possible Subtype of Dementia
J Geriatr Psychiatry Neurol, January 1, 1993; 6(1): 25 - 28.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
H. H. Funkenstein, M. S. Albert, N. R. Cook, C. G. West, P. A. Scherr, M. J. Chown, D. Pilgrim, and D. A. Evans
Extrapyramidal Signs and Other Neurologic Findings in Clinically Diagnosed Alzheimer's Disease: A Community-Based Study
Arch Neurol, January 1, 1993; 50(1): 51 - 56.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
H. Forstl, A. Burns, R. Levy, N. Cairns, P. Luthert, and P. Lantos
Neurologic Signs in Alzheimer's Disease: Results of a Prospective Clinical and Neuropathologic Study
Arch Neurol, October 1, 1992; 49(10): 1038 - 1042.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
R. Mayeux, J. Denaro, N. Hemenegildo, K. Marder, M.-X. Tang, L. J. Cote, and Y. Stern
A Population-Based Investigation of Parkinson's Disease With and Without Dementia: Relationship to Age and Gender
Arch Neurol, May 1, 1992; 49(5): 492 - 497.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
D. P. Devanand, L. Miller, M. Richards, K. Marder, K. Bell, R. Mayeux, and Y. Stern
The Columbia University Scale for Psychopathology in Alzheimer's Disease
Arch Neurol, April 1, 1992; 49(4): 371 - 376.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
J.-Y. Chen, Y. Stern, M. Sano, and R. Mayeux
Cumulative Risks of Developing Extrapyramidal Signs, Psychosis, or Myoclonus in the Course of Alzheimer's Disease
Arch Neurol, November 1, 1991; 48(11): 1141 - 1143.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
M. Richards, K. Marder, K. Bell, G. Dooneief, R. Mayeux, and Y. Stern
Interrater Reliability of Extrapyramidal Signs in a Group Assessed for Dementia
Arch Neurol, November 1, 1991; 48(11): 1147 - 1149.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
L. Ganzini, R. Heintz, W. F. Hoffman, G. A. Keepers, and D. E. Casey
Acute Extrapyramidal Syndromes in Neuroleptic-Treated Elders: A Pilot Study
J Geriatr Psychiatry Neurol, October 1, 1991; 4(4): 222 - 225.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
L. A. Farrer, L. A. Cupples, L. Connor, P. A. Wolf, and J. H. Growdon
Association of Decreased Paternal Age and Late-Onset Alzheimer's Disease: An Example of Genetic Imprinting?
Arch Neurol, June 1, 1991; 48(6): 599 - 604.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
S. Patel, P. N. Tariot, and R. W. Hamill
Pisa Syndrome Without Neuroleptic Exposure in a Patient With Dementia of the Alzheimer Type
J Geriatr Psychiatry Neurol, January 1, 1991; 4(1): 48 - 51.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
P. J. Tyrrell, G. V. Sawle, V. Ibanez, P. M. Bloomfield, K. L. Leenders, R. S. Frackowiak, and M. N. Rossor
Clinical and Positron Emission Tomographic Studies in the 'Extrapyramidal Syndrome' of Dementia of the Alzheimer Type
Arch Neurol, December 1, 1990; 47(12): 1318 - 1323.
[Abstract] [PDF]

Home page
 AM J ALZHEIMERS DIS OTHER DEMENHome page
S. H. Zarit and C. R. Goodman
Decision making and dementia
American Journal of Alzheimer's Disease and Other Dementias, September 1, 1990; 5(5): 22 - 28.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
D. A. Drachman, B. F. O'Donnell, R. A. Lew, and J. M. Swearer
The Prognosis in Alzheimer's Disease: 'How Far' Rather Than 'How Fast' Best Predicts the Course
Arch Neurol, August 1, 1990; 47(8): 851 - 856.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
W. J. Jagust, B. R. Reed, J. P. Seab, and T. F. Budinger
Alzheimer's Disease: Age at Onset and Single-Photon Emission Computed Tomographic Patterns of Regional Cerebral Blood Flow
Arch Neurol, June 1, 1990; 47(6): 628 - 633.
[Abstract] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
R. E. Donnelly and H. Karlinsky
The Impact of Alzheimer's Disease on Driving Ability: A Review
J Geriatr Psychiatry Neurol, April 1, 1990; 3(2): 67 - 72.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
F. Lai and R. S. Williams
A Prospective Study of Alzheimer Disease in Down Syndrome
Arch Neurol, August 1, 1989; 46(8): 849 - 853.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
J. C. Morris, M. Drazner, K. Fulling, E. A. Grant, and J. Goldring
Clinical and Pathological Aspects of Parkinsonism in Alzheimer's Disease: A Role for Extranigral Factors?
Arch Neurol, June 1, 1989; 46(6): 651 - 657.
[Abstract] [PDF]

Home page
 AM J ALZHEIMERS DIS OTHER DEMENHome page
D. P. Dastoor and M. G. Cole
Age related patterns of decline in dementia as measured by the hierarchic dementia scale (HDS)
American Journal of Alzheimer's Disease and Other Dementias, November 1, 1988; 3(6): 29 - 35.
[PDF]

Home page
 ANN INTERN MEDHome page
R. P. Friedland, E. Koss, J. V. Haxby, C. L. Grady, J. Luxenberg, M. B. Schapiro, and J. Kaye
Alzheimer Disease: Clinical and Biological Heterogeneity
Ann Intern Med, August 15, 1988; 109(4): 298 - 311.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
J. Botwinick, M. Storandt, L. Berg, and S. Boland
Senile Dementia of the Alzheimer Type: Subject Attrition and Testability in Research
Arch Neurol, May 1, 1988; 45(5): 493 - 496.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
J. R. Atack, M. F. Beal, C. May, J. A. Kaye, M. F. Mazurek, A. D. Kay, and S. I. Rapoport
Cerebrospinal Fluid Somatostatin and Neuropeptide Y: Concentrations in Aging and in Dementia of the Alzheimer Type With and Without Extrapyramidal Signs
Arch Neurol, March 1, 1988; 45(3): 269 - 274.
[Abstract] [PDF]

Home page
 Neurorehabil Neural RepairHome page
E. LaBarge, L. S. Rosenman, K. Leavitt, and T. Cristiani
Counseling Clients with Mild Senile Dementia of the Alzheimer's Type: A Pilot Study
Neurorehabil Neural Repair, January 1, 1988; 2(4): 167 - 173.
[Abstract] [PDF]

Home page
 ANN INTERN MEDHome page
R. J. KIERNAN, J. MUELLER, J. W. LANGSTON, and C. VAN DYKE
The Neurobehavioral Cognitive Status Examination: A Brief But Differentiated Approach to Cognitive Assessment
Ann Intern Med, October 1, 1987; 107(4): 481 - 485.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
F. J. Huff, F. Boller, F. Lucchelli, R. Querriera, J. Beyer, and S. Belle
The Neurologic Examination in Patients With Probable Alzheimer's Disease
Arch Neurol, September 1, 1987; 44(9): 929 - 932.
[Abstract] [PDF]

Home page
 Arch Gen PsychiatryHome page
W. Bondareff, C. Q. Mountjoy, M. Roth, M. N. Rossor, L. L. Iversen, and G. P. Reynolds
Age and Histopathologic Heterogeneity in Alzheimer's Disease: Evidence for Subtypes
Arch Gen Psychiatry, May 1, 1987; 44(5): 412 - 417.
[Abstract] [PDF]

Home page
 Journal of Applied GerontologyHome page
L. Volicer, B. Seltzer, Y. Rheaume, K. Fabiszewski, L. Herz, R. Shapiro, and P. Innis
Progression of Alzheimer-Type Dementia in Institutionalized Patients: A Cross-Sectional Study
Journal of Applied Gerontology, March 1, 1987; 6(1): 83 - 94.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
J. Botwinick, M. Storandt, and L. Berg
A Longitudinal, Behavioral Study of Senile Dementia of the Alzheimer Type
Arch Neurol, November 1, 1986; 43(11): 1124 - 1127.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
J. Leverenz and S. M. Sumi
Parkinson's Disease in Patients With Alzheimer's Disease
Arch Neurol, July 1, 1986; 43(7): 662 - 664.
[Abstract] [PDF]

Home page
 AM J ALZHEIMERS DIS OTHER DEMENHome page
M. Schweber
Etiologic theories of Alzheimer's disease
American Journal of Alzheimer's Disease and Other Dementias, January 1, 1986; 1(1): 24 - 31.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1985 by AAN Enterprises, Inc.