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Reversible ischemic attacks with normal angiogram

Risk factors, clinical findings, and prognosis

Neurological Clinic II (Drs. Landi, Guidotti, Pinciroli), Universityof Milan; Department of Neuroradiology (Dr. Scialfa), Niguarda Hospital; and Instititute of Biometry and Medical Statistics (Prof. Morabito), University of Milan, Milan, Italy.

One hundred seventeen patients with reversible ischemic attacks were divided into two groups according to the presence of atheromatous lesions on angiography. Female sex, vertebrobasilar territory involvement, and younger age were related to normal angiograms. Among risk factors, only hypertension was associated with atheroma. However, the number of risk factors in each patient was related linearly to angiographic abnormality. Later stroke and myocardial infarction were significantly more common in patients with atheromatous lesions.

Address correspondence and reprint requests to Dr. Landi, Università di Milano, Ospedale Maggiore—Policlinico, Clinica Neurologica II, Via F. Sforza N. 35, 20122 Milano, Italy.

Accepted for publieation July 17, 1984.