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NEUROLOGY 1985;35:405
© 1985 American Academy of Neurology

Cerebral vasculitis and hemorrhage associated with phenylpropanolamine

Robert J. Fallis, MD and Mark Fisher, MD

Department of Neurology, University of Southern California School of Medicine, Los Angeles, CA.

A 20-year-old woman using an oral diet aid preparation containing phenylpropanolamine presented with an intracerebral hemorrhage and angiographic evidence of cerebral vaculitis. Gas chromatography demonstrated phenylpropanolamine in the urine. Even when used within recommended guidelines, phenylpropanolamine usage should be included in the differential diagnosis of patients presenting with intracranial hemorrhage.

Address correspondence and reprint requests to Dr. Fisher, Department of Neurology, Room 5641, Unit 1, USC School of Medicine, 1200 North State Street, Los Angeles. CA 90033.

Dr. Fisher is recipient of Teacher-Investigator Development Award # 1K07 NS00884-01.

Accepted for publication July 17, 1984




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