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Sleep disturbances and severity of Huntington's disease

From the Marshfield Clinic, Marshfield, WI.

We studied sleep functions in two patients with mild and five with moderately severe Huntington's disease. In mild disease there was chorea, but intelligence, mental function, and sleep were all normal. In moderately severe disease, intelligence and mental function were also affected, and there was a sleep disturbance characterized by prolonged sleep-onset latency, increased interspersed wakefulness, and reduced sleep efficiency.

Address correspondence and reprint requests to Dr. Hansotia, Marshfield Clinic, 1000 North Oak Avenue, Marshfield, WI 54449-5777.

Presented in part at the thirty-sixth annual meeting of the American Academy of Neurology, Boston, MA, April 1984.

Accepted for publication March 7,1985.

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